Coronary calcification: Achilles’ heel in the assessment for coronary artery disease in patients with symptomatic angina?

Makaryus, John N.; Makaryus, Amgad N.

doi:10.1007/s10554-009-9535-1

Cited by 3 publications

(1 citation statement)

References 14 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Theoretically, the 100-kV protocol is more subject to the influence of calcification because the low tube voltage setting increases blooming artifacts of calcification [39,40]. Interestingly, although the frequencies of degraded segments with blurring of calcification were not significantly different in the present study, nonevaluable segments due to blurring of calcification were more common for the 100-kV protocol than for the 120-kV protocol.…”

Section: Discussioncontrasting

confidence: 61%

320-row CT coronary angiography: effect of 100-kV tube voltages on image quality, contrast volume, and radiation dose

Zhang

et al. 2010

Int J Cardiovasc Imaging

View full text Add to dashboard Cite

To prospectively evaluate image quality parameters, contrast volume and radiation dose at the 100-kilovolt (kV) setting during coronary computed tomographic angiography (CCTA) on a 320-row computed tomography scanner. We enrolled 107 consecutive patients with a heart rate <65 beats per minute (bpm) undergoing prospective electrocardiogram (ECG)-triggered CCTA. Forty patients with a body mass index (BMI) <25 kg/m(2) were scanned using 100-kV tube voltage settings, while 67 patients were scanned using 120-kV protocols. Image quality was assessed by two readers unaware of patient information and scan parameters. Attenuation in the aorta and perivascular fat tissue and image noise were measured. Contrast-to-noise ratios (CNRs) and contrast material volumes were calculated. The effective radiation doses were estimated using a chest conversion coefficient (0.017). Diagnostic image quality was achieved in 98.2% of coronary segments with 100-kV CCTA and 98.6% of coronary segments with 120-kV CCTA, with no significant differences in image quality scores for each coronary segment. Vessel attenuation, image noise, and CNR were not significantly different between the 100- and 120-kV protocols. Mean contrast injection rate and mean material volume were significantly lower for the 100-kV CCTA (4.35 ± 0.28 ml/s and 53.13 ± 3.77 ml, respectively) than for the 120-kV CCTA (5.16 ± 0.21 ml/s and 62.40 ± 3.66 ml respectively; P < 0.001). The effective radiation dose was 2.12 ± 0.19 mSv for 100-kV CCTA, a reduction of 54% compared to 4.61 ± 0.82 mSv for 120-kV CCTA. A 100-kV CCTA can be implemented in patients with a BMI < 25 kg/m(2). The 100-kV setting allows significant reductions in contrast material volume and effective radiation dose while maintaining adequate diagnostic image quality.

show abstract

Section: Discussioncontrasting

confidence: 61%