Diagnostic imaging of hepatic lymphoma

Abé, Hiroyuki; Kamimura, Kenya; Kawai, Hirokazu; Kamimura, Hiroteru; Domori, Koji; Kobayashi, Yuji; Nomoto, Minoru; Aoyagi, Yoshinobu

doi:10.1016/j.clinre.2014.11.001

Cited by 16 publications

(20 citation statements)

References 46 publications

(56 reference statements)

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“…Solid, hypodense, nodular lesions are also seen in hepatic lymphoma but existence of lymphadenopaties with periportal location of the lesions and disruption of the vascular architecture are helpful in making the differential diagnosis. Hepatic involvement in lymphoma is often seen as a secondary form in patients with known disease [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

CT of Hepatic Sarcoidosis: Small Nodular Lesions Simulating Metastatic Disease

Ufuk

Herek

2015

Pol J Radiol

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SummaryBackgroundSarcoidosis is a multisystemic inflammatory disease of unknown origin. The lymphoid system and the lungs are the most commonly involved organs. The frequency of signs or symptoms of hepatic involvement is very low.Case ReportWe present a case of symptomatic granulomatous liver disease secondary to sarcoidosis, mimicking a metastatic disease on ultrasonography and CT.ConclusionsHepatic involvement in sarcoidosis might be a perplexing diagnostic problem. The decisive CT finding with respect to the differential diagnosis was the absence of a mass effect and intact vascular architecture around the lesions.

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Section: Discussionmentioning

confidence: 99%

CT of Hepatic Sarcoidosis: Small Nodular Lesions Simulating Metastatic Disease

Ufuk

Herek

2015

Pol J Radiol

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“…Hepatosplenic T-cell lymphoma is a rare and poorly recognized entity characterized by neoplastic proliferation of T-cells in hepatic sinusoids and splenic red pulp without lymphadenopathy and bone marrow involvement [ 22 – 26 ]. More recently, hepatic involvement by the intravascular variety of lymphoma has also been described caused by neoplastic proliferation in the lumen of small- to medium-sized hepatic vessels [ 27 , 28 ]. However, due to paucity of literature on these forms of lymphoma, no specific imaging features have been recognized.…”

Section: Other Forms Of Lymphomamentioning

confidence: 99%

“…Lymphomatous involvement of liver can manifest on imaging as solitary or multiple nodular lesions, diffuse infiltration, or as a periportal soft tissue mass [ 15 , 28 , 29 ]. A combination of infiltrating and nodular patterns has also been described.…”

Section: Imaging Featuresmentioning

confidence: 99%

The imaging conundrum of hepatic lymphoma revisited

et al. 2015

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The imaging manifestations of hepatic lymphoma, both in its primary and secondary form, are extremely variable and overlap with a number of other more common hepatic diseases. However, in the appropriate clinical context, combining the imaging and laboratory features can aid in making the correct diagnosis. Since the management and prognosis of lymphomas are significantly different from other malignancies, early diagnosis and prompt commencement of therapy is of paramount importance. The various morphological appearances of hepatic lymphoma on imaging have been described here along with their possible differentials.Teaching points• Primary hepatic lymphoma is extremely rare.• Secondary liver involvement occurs in 50 % of patients with non-Hodgkin lymphoma.• The imaging manifestations of hepatic lymphoma are largely non-specific.• Some imaging features may be helpful in the appropriate clinical setting.• Management and prognosis of lymphoma is significantly different from other malignancies.

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“…The primary hepatic lymphoma accounts for less than 1% of all cases of lymphoma and occurs when lymphoma is confined to the liver, without disease in the lymph nodes, spleen, bone marrow, or other lymphomatous structures [ 42 - 43 ]. The majority of patients present with multiple lesions, though up to one third may have a solitary lesion.…”

Section: Reviewmentioning

confidence: 99%

“…The majority of patients present with multiple lesions, though up to one third may have a solitary lesion. The MRI appearance of these lesions is nonspecific, as lesions have a T1 hypointense and T2 mildly hyperintense signal and enhance less than the adjacent hepatic parenchyma (Figure 16 - 17 ) [ 42 , 44 ]. More rarely, a diffuse, infiltrative pattern has also been described, which may present as an enlarged liver with indistinct lesions [ 42 , 45 ].…”

Section: Reviewmentioning

confidence: 99%

Magnetic Resonance Imaging of Primary Hepatic Malignancies in Patients With and Without Chronic Liver Disease: A Pictorial Review

Alexander¹,

Harri²,

Little³

et al. 2017

Cureus

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Primary hepatic malignancies are less common than metastatic diseases, but a recognition of these lesions is important for diagnosis and treatment planning. Magnetic resonance imaging (MRI) provides the most imaging information to diagnose lesions noninvasively and to narrow differential diagnoses. This paper reviews the imaging findings of chronic liver disease and primary hepatic malignancies, including hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (CCA), epithelioid hemangioendothelioma, hepatic angiosarcoma, and primary hepatic lymphoma. Clinical and MRI features are reviewed to improve the readers’ recognition of these tumors, allowing for a narrower differential diagnosis when liver masses are encountered on abdominal imaging.

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Diagnostic imaging of hepatic lymphoma

Cited by 16 publications

References 46 publications

CT of Hepatic Sarcoidosis: Small Nodular Lesions Simulating Metastatic Disease

CT of Hepatic Sarcoidosis: Small Nodular Lesions Simulating Metastatic Disease

The imaging conundrum of hepatic lymphoma revisited

Magnetic Resonance Imaging of Primary Hepatic Malignancies in Patients With and Without Chronic Liver Disease: A Pictorial Review

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