Diagnostic Imaging in Patients with Orbital Cellulitis and Inflammatory Pseudotumor

Uehara, F; Ohba, N

doi:10.1097/00004397-200201000-00017

Cited by 23 publications

(21 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Typically, OIS lesions are described as isointense to extraocular muscle on T1-weighted images but can show variability, which is consistent with our findings. 2,3,6 T2 signal intensity in OIS lesions was less predictable, both in this study and in the literature. 2 OIS lesions showed contrast enhancement, consistent with the literature.…”

Section: Discussioncontrasting

confidence: 61%

“…1 Other processes, specifically orbital lymphoid lesions and orbital cellulitis, can frequently masquerade as OIS. 2–5 …”

mentioning

confidence: 99%

“…OIS generally presents more acutely, with symptoms of proptosis, extraocular motility disturbance, pain, erythema, and chemosis. 2 Nonetheless, all of these features can be common to both OIS and orbital lymphoid lesions with a variable onset seen in both processes. Orbital lymphoid lesion commonly presents as a mass on CT and MR imaging.…”

mentioning

confidence: 99%

“…Previous descriptive analyses comparing OIS and lymphoma, and comparing OIS and orbital cellulitis on MR imaging, did not show differences specific enough for differentiating these diseases. 2,6 …”

mentioning

confidence: 99%

See 3 more Smart Citations

MR Imaging of Orbital Inflammatory Syndrome, Orbital Cellulitis, and Orbital Lymphoid Lesions: The Role of Diffusion-Weighted Imaging

Kapur

Sepahdari²,

Mafee³

et al. 2008

AJNR Am J Neuroradiol

159

View full text Add to dashboard Cite

BACKGROUND AND PURPOSE Orbital inflammatory syndrome (OIS) has clinical features that overlap with orbital lymphoid lesions and orbital cellulitis. Prompt diagnosis is needed in all 3 conditions because the management of each one differs greatly. CT and MR imaging, though useful, do not always distinguish among these conditions. The aim of this study was to identify the role of diffusion-weighted imaging (DWI) in differentiating these 3 diagnoses. MATERIALS AND METHODS A retrospective analysis of orbital MR imaging was conducted. T1- and T2-weighted and postcontrast images were analyzed. Region-of-interest analysis was performed by using measurements in areas of abnormality seen on conventional MR imaging sequences and measurements of the ipsilateral thalamus for each patient. The DWI signal intensity of the lesion was expressed as a percentage of average thalamic intensity in each patient. Similarly, lesion apparent diffusion coefficients (ADCs) and lesion-thalamus ADC ratios were calculated. Statistical significance was determined by the Kruskal-Wallis test, and post hoc pairwise comparisons, by the Mann-Whitney U test for DWI-intensity ratio, ADC, and ADC ratio. RESULTS A significant difference was noted in DWI intensities, ADC, and ADC ratio between OIS, orbital lymphoid lesions, and orbital cellulitis (P < .05). Lymphoid lesions were significantly brighter than OIS, and OIS lesions were significantly brighter than cellulitis. Lymphoid lesions showed lower ADC than OIS and cellulitis. A trend was seen toward lower ADC in OIS than in cellulitis (P = .17). CONCLUSIONS DWI may help differentiate OIS from lymphoid lesions and cellulitis and may allow more rapid management.

show abstract

Section: Discussioncontrasting

confidence: 61%

“…1 Other processes, specifically orbital lymphoid lesions and orbital cellulitis, can frequently masquerade as OIS. 2–5 …”

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

MR Imaging of Orbital Inflammatory Syndrome, Orbital Cellulitis, and Orbital Lymphoid Lesions: The Role of Diffusion-Weighted Imaging

Kapur

Sepahdari²,

Mafee³

et al. 2008

AJNR Am J Neuroradiol

159

View full text Add to dashboard Cite

show abstract

“…Orbital cellulitis is a potentially life-threatening disease often associated with antecedent sinus disease, dental procedures, or trauma and is typically accompanied by fever and leukocytosis, features that are uncommon in noninfectious OID. 40,52,53,56,59,60 These patients are generally hospitalized for intensive, broad-spectrum intravenous antimicrobial therapy pending identification of the inciting organism. The correct diagnosis of OID may occur only after a lack of response to the presumptive treatment of an underlying infection and exquisite sensitivity to systemic corticosteroids.…”

Section: Orbital Involvement In Oidmentioning

confidence: 99%