Diagnostic accuracy of FDG PET in the follow-up of platinum-sensitive epithelial ovarian carcinoma

Abstract

FDG PET may detect recurrent ovarian cancer earlier than CIM, with higher sensitivity and even higher diagnostic accuracy.

Impact of FDG PET in optimizing patient selection for cytoreductive surgery in recurrent ovarian cancer

“…[8][9][10] And the sensitivity and specificity of PET-CT are 93.3-97.4% and 80-100%, respectively. [11,12] A recent meta-analysis of 29 studies demonstrated that PET-CT had high sensitivity (89%) and specificity (90%).…”

The Role of 18F-FDG PET in Assessing Therapy Response in Cancer of the Cervix and Ovaries

“…The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of 18 F-FDG PET were 87%, 79%, 85%, 92%, and 68%, respectively, compared with 53%, 82%, 61%, 89%, and 39%, respectively, for conventional imaging and 58%, 94%, and 67%, respectively, for CA-125 measurements (50). In 23 of 55 patients with positive serum CA-125 levels but negative conventional imaging findings, 18 F-FDG PET was positive and relapse was confirmed.…”

Follow-Up of Patients Who Are Clinically Disease-Free after Primary Treatment for Fallopian Tube, Primary Peritoneal, or Epithelial Ovarian Cancer: A Program in Evidence-Based Care Guideline Adaptation

“…Twelve full-text studies constituted the evidence base for t he present g u ideline : one rct of c a125 i n fol low-up 15 ; five retrospective cohort studies on methods of detection [16][17][18][19][20] ; two pilot studies 21,22 ; and four qualitative or observational studies of psychosocial concerns, health care provider and patient preferences or satisfaction, and patterns of care [23][24][25][26] . Eleven of those studies fell within the scope of our guideline; one study about sexual symptomatology was out-of-scope 22 …”