Diagnosis of melanoma using optical coherence tomography

Abstract

Главными причинами высокой летальности при меланоме являются несвоевременная диагностика с развитием инвазивных форм и ошибки диагностики, приводящие к неадекватному вмешательству.

Experience of using 3D-OCT for visualization of vessels in skin neoplasms

“…In the images of horizontal sections of the tumor at the level of the upper dermis, this pattern, consisting in the predominant location of vessels in the marginal zone of the tumor and a larger diameter of vessels in its peripheral part, was even more obvious. The analysis of 85 images of vertical sections of the central and peripheral parts of nodular melanoma obtained during the examination of 10 patients revealed OCT signs of this disease [4] in the form of an increase in the total height of the image layers with the absence of visualization of the layers themselves, a significant increase in the depth of the useful signal, but a weakening of its intensity within the tumor (Figure 3.4). As in the case of basal cell carcinoma, numerous dilated vessels were visualized within the tumor, the concentration of which was higher in the peripheral part of the neoplasm.…”