Diagnosis of Early Lattice Corneal Dystrophy

Dubord, Paul; Krachmer, Jay H.

doi:10.1001/archopht.1982.01030030792013

Cited by 20 publications

(6 citation statements)

References 11 publications

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“…Dubord and Krachmer [2] examined seven children with lattice corneal dystrophy whose corneae showed subepithelial white opacity, diffuse axial anterior stromal haze and filamentary lines. In case 4, who was 12 years old, slit lamp examination disclosed only diffuse central anterior stromal opacity and no dots or filamentary lines.…”

Section: Discussionmentioning

confidence: 44%

Specular microscopic findings of lattice corneal dystrophy

et al. 1987

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A Japanese family with 4 members suffering from lattice dystrophy of the cornea is reported. Their central corneas were affected leaving the peripheral zone clear. Corneal lesions were found in the superficial stroma of younger cases and in the deeper stroma of older cases. The proband was a 75 year-old woman who underwent a penetrating keratoplasty. Her corneal specimens revealed amyloid deposits stained with Congo red in the stroma. In specular microscopy, the probands central cornea had a crateriform appearance which had not been reported in the literatures. A few fine short branching lines and crateriform lesions were shown in the superficial stroma of the proband's daughter and only crisscrossing lines could be seen in her granddaughter's cornea.

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Section: Discussionmentioning

confidence: 44%

Specular microscopic findings of lattice corneal dystrophy

et al. 1987

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“…Our obser vations revealed that the degree of accumula tion of fibrocellular connective tissue was unrelated to the amount of stromal amyloid material deposited. The subepithelial opaci ties may become clinically apparent earlier than the stromal lattice figures [8]. In some reported pedigrees of LCD the presence of family members with recurrent corneal ero sions and superficial central leukoma without evidence of stromal refractile lines has been noted [17], The severity of subepithelial opacities associated with a few, fine lattice lines, easy to overlook, may be misleading in the absence of family history of an inherited corneal disorder [ 17], Histopathologically, the subepithelial opacities are composed of a variable mixture of collagen fibers, fibrillar material, amyloid, elastotic concretions and active fibroblasts.…”

Section: Discussionmentioning

confidence: 48%

“…except by isolated reports [4,5], have briefly been mentioned in major reviews on the subject. Most authors pointed toward the nonhomogeneous struc ture of the deposits and agreed that the subepithelial changes are the result of a nonspe cific tissue response [6][7][8],…”

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confidence: 42%

Superficial Involvement in Lattice Corneal Dystrophy

Em¹,

Jo²,

Es³

1986

Ophthalmologica

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Twenty-one corneas with lattice dystrophy were studied histologically to evaluate the magnitude of superficial lesions. The compromise included epithelium disarray and atrophy, degenerative pannus, disruption and absence of Bowman’s layers, amyloid deposits, and elastotic deposits. These changes were progressive according to patients’ age at time of keratoplasty. Oxytalan fibers, an elastic component, were found in affected corneas. The relation of these fibers to elastotic deposition and abnormal fibrillogenesis in lattice corneal dystrophy is discussed.

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“…Despite the fact that this dystrophy may recur in the corneal grafts, severe cases of lattice dystrophy with decreased vision can be treated with lamellar keratoplasty (DALK) or Penetrating Keratoplasty (PK). [56,[70][71][72][73][74][75][76][77][78][79]…”

Section: Lattice Dystrophy Type ( I )mentioning

confidence: 99%

Ocular Presentations of Amyloidosis

Hashemian¹,

Jabbarvand²,

Khodaparast³

et al. 2013

Amyloidosis

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Please use Adobe Acrobat Reader to read this book chapter for free. Just open this same document with Adobe Reader. If you do not have it, you can download it here. You can freely access the chapter at the Web Viewer here. tis, or immune conjunctival involvements like GVHD can lead to secondary conjunctival Amyloidosis, this is not a common phenomenon. (a) (b) Amyloidosis 96 Please use Adobe Acrobat Reader to read this book chapter for free. Just open this same document with Adobe Reader. If you do not have it, you can download it here. You can freely access the chapter at the Web Viewer here.

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Diagnosis of Early Lattice Corneal Dystrophy

Cited by 20 publications

References 11 publications

Specular microscopic findings of lattice corneal dystrophy

Specular microscopic findings of lattice corneal dystrophy

Superficial Involvement in Lattice Corneal Dystrophy

Ocular Presentations of Amyloidosis

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