Diagnosis of diabetes mellitus: reiterated responsibilities for the clinical laboratory

Gillery, Philippe; Lippi, Giuseppe; Plebani, Mario

doi:10.1515/cclm-2014-0443

Cited by 3 publications

(1 citation statement)

References 13 publications

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“…Diabetes mellitus (DM) is a heavy burden for patients worldwide, and the number of affected individuals is growing significantly. By 2030, it is estimated that it will affect almost 552 million [ 1 ]. High glucose is the initiating factor of DM and a series of complications, the mechanisms of which are intricate and complex.…”

Section: Introductionmentioning

confidence: 99%

The Effects of Chinese Medicine on Activation of Wnt/β-Catenin Signal Pathway under High Glucose Condition

Liu

Liang

Yang

2015

Evidence-Based Complementary and Alternative Medicine

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Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycemia and a series of complications. The Wnt/β-catenin signaling pathway is a complex protein interaction network, which is also a key regulator of cell proliferation and differentiation. Many scholars have found that high glucose can activate the Wnt signaling pathway. However, the effects of activation of this pathway in the presence of high glucose levels during the progression of diabetes still remained unclear. Here, we provide a review of the study on the effects of high glucose state on the Wnt/β-catenin signal pathway and the influence of Chinese medicine on it.

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Section: Introductionmentioning

confidence: 99%

The Effects of Chinese Medicine on Activation of Wnt/β-Catenin Signal Pathway under High Glucose Condition

Liu

Liang

Yang

2015

Evidence-Based Complementary and Alternative Medicine

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AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose

Zhang

Huang³

et al. 2021

Biomedicine & Pharmacotherapy

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HbA_1c and biomarkers of diabetes mellitus in Clinical Chemistry and Laboratory Medicine: ten years after

Gillery

2022

Clinical Chemistry and Laboratory Medicine (CCLM)

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Since its discovery in the late 1960s, HbA1c has proven to be a major biomarker of diabetes mellitus survey and diagnosis. Other biomarkers have also been described using classical laboratory methods or more innovative, non-invasive ones. All biomarkers of diabetes, including the historical glucose assay, have well-controlled strengths and limitations, determining their indications in clinical use. They all request high quality preanalytical and analytical methodologies, necessitating a strict evaluation of their performances by external quality control assessment trials. Specific requirements are needed for point-of-care testing technologies. This general overview, which describes how old and new tools of diabetes mellitus biological survey have evolved over the last decade, has been built through the prism of papers published in Clinical Chemistry and Laboratory Medicine during this period.

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Diagnosis of diabetes mellitus: reiterated responsibilities for the clinical laboratory

Cited by 3 publications

References 13 publications

The Effects of Chinese Medicine on Activation of Wnt/β-Catenin Signal Pathway under High Glucose Condition

The Effects of Chinese Medicine on Activation of Wnt/β-Catenin Signal Pathway under High Glucose Condition

AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose

HbA_1c and biomarkers of diabetes mellitus in Clinical Chemistry and Laboratory Medicine: ten years after

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Diagnosis of diabetes mellitus: reiterated responsibilities for the clinical laboratory

Cited by 3 publications

References 13 publications

The Effects of Chinese Medicine on Activation of Wnt/β-Catenin Signal Pathway under High Glucose Condition

The Effects of Chinese Medicine on Activation of Wnt/β-Catenin Signal Pathway under High Glucose Condition

AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose

HbA1c and biomarkers of diabetes mellitus in Clinical Chemistry and Laboratory Medicine: ten years after

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HbA_1c and biomarkers of diabetes mellitus in Clinical Chemistry and Laboratory Medicine: ten years after