Diagnosis and Treatment of Urothelial Tumors by Ureteropyeloscopy

Papadopoulos, Iordanis N.; Wirth, Barbara; Bertermann, H.; Wand, Handan

doi:10.1089/end.1990.4.55

Cited by 10 publications

(4 citation statements)

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“…Since then, endoscopic diagnosis and treatment have been performed increasingly in many patients with upper tract lesions. 8,9,16,19,22,23 In our 15 patients, renal pelvic carcinoma was diagnosed in four patients (26.7%), one of 11 patients with hematuria (9.1%) and three of four patients with hematuria and a filling defect (75.0%). Reported frequencies of upper tract TCC diagnosed by ureteropyeloscopy are 0-68.4% in patients with hematuria, 8,13,19,20 12.5-66.7% in patients with a filling defect on urography 8,13,15,18,20 and 66.7% in patients with hematuria and a filling defect on urography.…”

Section: Discussionmentioning

confidence: 77%

“…The most important disease of the upper tract that should be diagnosed accurately is urothelial carcinoma of the renal pelvis and ureter. Diagnosis of upper tract urothelial carcinoma is sometimes elusive with standard diagnostic methods 18 , 23 , 24 . In such cases, a diagnosis of urothelial carcinoma of the upper tract is challenging.…”

Section: Discussionmentioning

confidence: 99%

“…Huffman et al 13 reported on the endoscopic diagnosis and management of an upper tract urothelial tumor in 1985. Since then, endoscopic diagnosis and treatment have been performed increasingly in many patients with upper tract lesions 8 , 9 , 16 , 19 , 22 , 23 …”

Section: Discussionmentioning

confidence: 99%

“…Diagnosis of upper tract urothelial carcinoma is sometimes elusive with standard diagnostic methods. 18,23,24 In such cases, a diagnosis of urothelial carcinoma of the upper tract is challenging. Huffman et al 13 reported on the endoscopic diagnosis and management of an upper tract urothelial tumor in 1985.…”

Section: Discussionmentioning

confidence: 99%

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Ureteropyeloscopy in the diagnosis of patients with upper tract hematuria: An initial clinical study

et al. 1999

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Background: To study the usefulness and safety of ureteropyeloscopy in the diagnosis of upper tract hematuria of unknown etiology by standard diagnostic methods. Methods: Fifteen patients with upper tract hematuria of unknown etiology were the subjects of the present study. Prior to ureteropyeloscopy, they underwent standard diagnostic methods, including cystourethroscopy, excretory urography and computed tomography scan. The upper tract (ureter, renal pelvis and calyces) was inspected systematically with a flexible ureteropyeloscope under epidural anesthesia. A biopsy specimen was obtained when neoplasm of a suspicious lesion was seen. Bleeding and hemangiomatous lesions were fulgurated at the time of ureteropyeloscopy. Results: Unilateral gross hematuria was seen in 12 patients. Imaging studies revealed a filling defect in four patients, ureteral stenosis in one patient and nutcracker phenomenon in one patient. Urine cytology was positive in three patients and suspicious in four patients. Results of ureteropyeloscopy were papillary tumor in three patients, whitish encrustation in one patient, redness of the renal pelvis in one patient, bleeding from the renal calyx in two patients, hemangiomatous lesion in one patient, ureteral stenosis in two patients and no abnormalities in five patients. Biopsies were performed in five patients. The pathology results were transitional cell carcinoma in four patients and no abnormality in one patient. Although a ureteral stent catheter was placed in one patient, no serious complications were encountered during or after the procedures. Conclusions: Ureteropyeloscopy was useful and relatively safe. This endoscopic examination can differentiate insignificant lesions from significant lesions by visual inspection of the lesions, in addition, pathological diagnosis by biopsy specimen can also be performed if deemed necessary. Ureteropyeloscopy is recommended in the diagnosis of upper tract hematuria of unknown etiology.

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