Diagnosis and Treatment of Sudden‐Onset Sensorineural Hearing Loss: A Study of 51 Patients

Zadeh, Mani H.; Storper, Ian S.; Spitzer, J.

doi:10.1067/mhn.2003.50

Cited by 146 publications

(141 citation statements)

References 13 publications

(60 reference statements)

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“…The patients that were seen within 1 week from onset of condition presented better hearing recovery rates, a similar finding to that of other authors 3,6 . The initial analysis of this piece of information could suggest that treatment is more effective than natural progression of the disease.…”

Section: Discussionsupporting

confidence: 79%

“…3,4,6 Differently from other authors, we did not find any correlation between type of audiometric curve or severity of hearing loss in auditory recovery 4 . There were patients with mild losses that did not recover hearing and others with profound loss who fully recovered it.…”

Section: Discussioncontrasting

confidence: 56%

“…3,[8][9][10] In our study, we used a previously defined protocol in all patients with SD that came to the Emergency room, and diagnosis of etiology was found in 30% of the cases. Other studies reported identification of etiology in only 10 to 15% of the cases 6,9 . These differences may be justified by the use of different clinical protocols that may have different sensitivity levels.…”

Section: Discussionmentioning

confidence: 99%

“…Ascending curves or those with predominance of medium frequencies did not show better prognosis in our sample than what was described in the literature. 6 The presence of associated symptoms, such as tinnitus and vertigo, was related with worse prognosis by many authors 3,4,16 . In our sample, vestibular symptoms of vertigo and imbalance were present in 52.5% of the patients, but the presence of tinnitus was greater than what had been reported by other authors 3,4 , affecting at the beginning of the presentation 100% of the patients.…”

Section: Discussionmentioning

confidence: 99%

“…Conversely, SD should be approached as an emergency, given that early intervention is associated with the best prognosis. 3,6 To contribute to the understanding of cases of SD and to promote better guidance in the cases of SD that were seen in our service, we conducted a prospective study for 2 years, analyzing the clinical and audiometric aspects, basic lab tests and imaging exams of these patients. The investigation of etiology of SD and the immediate observation of auditory progression regardless of the etiological diagnosis after the common initial treatment with prednisone and pentoxifylline were the main objectives of this study.…”

Section: Introductionmentioning

confidence: 99%

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Fatores clínicos, etiológicos e evolutivos da audição na surdez súbita

Penido

Ramos

Barros

et al. 2005

Rev. Bras. Otorrinolaringol.

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Out of the many forms of therapy for sudden deafness, some require hospitalization and present significant risks. Aim: This prospective study analyzes etiology and evolution in cases of sudden deafness (SD) where outpatient oral treatment was used. Study design: clinical with transversal cohort. Material and Method: Forty cases of sudden hearing loss were followed for at least one year. All were submitted to initial clinical evaluation, auditory tests, routine blood analysis, and magnetic resonance imaging. All received initial treatment with pentoxifylline and prednisone. Results: 45% (n=18) presented normal auditory thresholds, 40% (n=16) showed some improvement in hearing, 15% (n=6) maintained initial hearing level. Nine cases (22.5%) presented clinical conditions possibly implicated in hearing loss (viral infection, immunomediated hearing loss, vascular disorders, and so on); three (7.5%) had cerebellopontine tumors. Evolution of hearing in these 12 cases with presumed etiology presented no differences from hearing in the 28 cases without any known etiological factor. Clinical treatment within the first seven days was the only statistically significantly different condition in patients who improved hearing. Conclusions: An objective search for etiological bases should be conducted in any case of acute sensorineural hearing loss. The presence of cerebellopontine tumors in 7.5% of cases of SD, among other treated causes, justifies a thorough clinical investigation in these patients. Overall good evolution of hearing was observed in 67.5% of cases of SD, regardless of its etiology. Therapy within the first seven days of SD was significantly related to better outcomes in hearing.

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Section: Discussionsupporting

confidence: 79%

Section: Discussioncontrasting

confidence: 56%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Fatores clínicos, etiológicos e evolutivos da audição na surdez súbita

Penido

Ramos

Barros

et al. 2005

Rev. Bras. Otorrinolaringol.

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Idiopathic Sudden Sensorineural Hearing Loss in the Only Hearing Ear

Stahl

Cohen²

2006

Arch Otolaryngol Head Neck Surg

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To determine the otological outcome in patients with idiopathic sudden sensorineural hearing loss (ISSHL) in their only hearing ear.Design: Retrospective medical chart review study.Setting: Tertiary care hospital.Patients: Forty-five consecutive patients older than 18 years with sudden sensorineural hearing loss during a 10 year period (1985)(1986)(1987)(1988)(1989)(1990)(1991)(1992)(1993)(1994)(1995), 9 of whom had ISSHL in their only hearing ear.Intervention: Daily audiometric tests, oral prednisolone (full available dose), and bed rest for at least a week.Main Outcome Measure: The audiometric result 7 to 10 days following the start of treatment was used as the treatment outcome.Results: Demographic characteristics were not significantly different between patients with ISSHL whose contralateral ear is deaf and those whose contralateral ear hears well. A tendency to seek help sooner (2.8 ± 1.4 vs 7.1 ± 5.2 days [mean ± SD], respectively) was noted. The mean ± SD improvement of hearing in the 3 more affected frequencies was 13 ± 13.4 dB for the investigated group compared with 9±8.7dB for the rest of the patients (not statistically significant). Of the 9 patients who previously had sensorineural hearing loss in the opposite ear, 5 showed end results of speech reception thresholds of 35 dB or better, as did 13 of the 36 patients in the other group.

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