Diagnosis and treatment of pelvic congestion syndrome: UIP consensus document

Antignani, Pier-Luigi; Lazarashvili, Zaza; Monedero, Javier; Ezpeleta, S. Zubicoa; Whiteley, Mark S; Khilnani, Neil M.; Meissner, Mark H.; Wittens, Cees H. A.; Kurstjens, Ralph L. M.; Belova, L. A.; Bokuchava, Mamuka; Elkashishi, Wassila T; Jeanneret-Gris, Christina; Geroulakos, George; Gianesini, Sergio; Graaf, Rick de; Krzanowski, Marek; Tarazi, Louay Al; Tessari, L; Wikkeling, Marald

doi:10.23736/s0392-9590.19.04237-8

Cited by 104 publications

(89 citation statements)

References 85 publications

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“…A major complication of ovarian vein embolization is the non-target veins embolization, which may be caused by incorrected concentration ratio glue/coils used or protrusion. Another common complication is the migration of coils or glue fragments, which may be attributed to incorrect evaluation of pelvic vein diameter due to vasospasm [1,19]. Fortunately, neither complications were observed in our study, which likely might be attributed to the physicochemical property of Glubran-2 and the knowledge and experience of clinicians in employing Glubran-2.…”

Section: Discussionmentioning

confidence: 51%

“…Fortunately, neither complications were observed in our study, which likely might be attributed to the physicochemical property of Glubran-2 and the knowledge and experience of clinicians in employing Glubran-2. Moreover, ovarian vein embolization was found no signi cant changes in follicle stimulating hormone, luteinizing hormone, or estradiol levels, which were thought to be unassociated with pregnancy [1,18,20]. Data revealed that Glubran-2 used in postpartum hemorrhage was without adversely affect in uterine function when embolizing uterine arteries [21].…”

Section: Discussionmentioning

confidence: 94%

“…The safety is an important component for evaluation of ovarian vein embolization, and complications in such endovascular treatment are reported practically rare [1,5,6]. A major complication of ovarian vein embolization is the non-target veins embolization, which may be caused by incorrected concentration ratio glue/coils used or protrusion.…”

Section: Discussionmentioning

confidence: 99%

“…Chronic pelvic pain (CPP) secondary to pelvic congestion syndrome (PCS) is common only presented with a condition of non-cyclic pelvic pain greater than 6 months in duration, typically affecting 39% women in reproductive age (20-45 years) [1]. This chronic positional pain is variable in term of intensity and duration, is frequently accompanied by dyspareunia and urgent bladder irritability, which can extend to the posteromedial thigh or buttock and has an extremely negative impact on quality of life [2,3].…”

Section: Introductionmentioning

confidence: 99%

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Ovarian Vein Embolization with N-butyl-2 Cyanoacrylate Glubran-2® for the Treatment of Chronic Pelvic Pain Secondary to Pelvic Congestion Syndrome

Gong¹,

He²,

Zhao³

et al. 2020

Preprint

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Objective: To evaluate the safety and efficacy of ovarian vein embolization using N- butyl-2 cyanoacrylate (NBCA) Glubran-2® in the treatment of chronic pelvic pain (CPP) secondary to pelvic congestion syndrome (PCS).Materials and Methods: Between January 2013 and June 2019, seven wo-men (mean age, 45.6±15.9 y) presenting with CPP secondary to PCS were evaluated for ovarian vein embolization with Glubran-2®. PCS was initially diagnosed by transva-ginal Doppler Ultrasound or CT and further confirmed by pelvic venography. Medical database was retrospectively reviewed.Results: Glubran-2 was employed as a sole embolic material in two cases, four cases subsequently underwent added microcoils in the opening of varicose ovarian vein trunk during the same procedure. Secondary embolization was achieved in one case due to CPP recurrence one month after initial embolization with microcoils. Technical success of ovarian vein embolization with Glubran-2 was achieved in all patients. There were no Glubran-2 related complications mid procedure and postintervention. With mean 62±40 months (range, 12-102 months) follow-up, neither persistent nor recurrent CPP was observed. Clinical efficacy was evaluated on the 1st, 3rd, 6th, 12th months, complete or slight improvement of CPP after embolization were achieved in all patients. VAS score used to identify preintervention and postintervention significantly decreased (p<0.001). Two patients after Glubran-2 embolization gave birth to a healthy baby during follow-up.Conclusions: Ovarian vein embolization with Glubran-2 is a feasible and safe treatment of CPP secondary to PCS. In particularly, it appears to be a potential and attractive alternative when patients with the desires of symptom relief and reproduction.

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Section: Discussionmentioning

confidence: 51%

Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Ovarian Vein Embolization with N-butyl-2 Cyanoacrylate Glubran-2® for the Treatment of Chronic Pelvic Pain Secondary to Pelvic Congestion Syndrome

Gong¹,

He²,

Zhao³

et al. 2020

Preprint

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“…Trotz hochentwickelter Ultraschallmaschinen und einer Reihe verfügbarer Sonden (linear, konvex, vaginal) ist die Sen-sitivität eingeschränkt. Allerdings sind zum gegenwärtigen Zeitpunkt auch die radiologischen Schnittbildverfahren nicht eindeutig überlegen [20].…”

Section: Diagnostik Und Differenzialdiagnostik Des Pelvinen Stauungssunclassified

Pelvines Stauungssyndrom: Wie wird die Diagnose gesichert, wer muss behandelt werden?

Hirsch

Wohlgemuth

2020

Phlebologie

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ZusammenfassungUnterleibsbeschwerden waren lange Zeit die Domäne von Gynäkologen, Internisten und Urologen. Die Erkenntnis, dass auch eine venöse Abstrombehinderung im kleinen Becken bzw. im Abdomen ähnliche Beschwerden hervorrufen kann, hat dazu geführt, dass in den letzten Jahren auch Gefäßmediziner in die Diagnostik und Behandlung einbezogen werden.Das pelvine Stauungssyndrom kann eine Vielzahl von auch nichtspezifischen Beschwerden verursachen. Die differenzialdiagnostische Abgrenzung zu gynäkologischen, internistischen oder auch orthopädischen Störungen stellt damit eine Herausforderung dar. Die akribische Anamneseerhebung und Symptombeschreibung sind von übergeordneter Bedeutung. In der weiteren Diagnostik kommt der Sonografie die wichtigste Bedeutung zu, die durch radiologische Schichtbildverfahren ergänzt werden kann. Wird vor allem eine Varikose im Genitalbereich beklagt, ist zu klären, ob es sich um eine venöse Insuffizienz im Bereich der Vena iliaca interna bzw. der Vena ovarica handelt oder ob postthrombotische Veränderungen eine Rolle spielen. Bei pelvinen und abdominellen Schmerzzuständen müssen zusätzlich die Nierenvenen und die untere Hohlvene beurteilt werden.Nur wenn die Störung differenzialdiagnostisch sicher abgegrenzt werden kann, ist eine invasive Behandlung durch Katheterverfahren und/oder Schaumsklerotherapie angezeigt.

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