Diagnosis and Management of Endomyocardial Fibrosis

Beaton, Andrea; Mocumbi, Ana Olga

doi:10.1016/j.ccl.2016.08.005

Cited by 41 publications

(49 citation statements)

References 75 publications

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“…The worldwide prevalence of EMF has been estimated as 10-12 per million. 10 EMF has been reported from other subtropical countries; Egypt, 11 Nigeria, 9,12 Brazil, Kerala in India, 13,14 and Sudan. 15,16 It is exceedingly rare in Europe and North America; however few cases have been reported in China 17 and Japan.…”

Section: Epidemiologymentioning

confidence: 95%

“…7 Some of those additional factors prevail in other non-African tropical and subtropical countries like Brazil and India where EMF has been reported. 9,10 In Africa, patients in endemic areas suffer from malnutrition, additionally, they consume cassava, which contains the earth element Cerium. It is reported that Cerium and hypomagnesemia in combination may induce EMF-like disease in experimental animals.…”

Section: Etiologymentioning

confidence: 99%

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<p>Endomyocardial Fibrosis: Diagnosis and Management</p>

Khalil¹

2020

JVD

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Section: Epidemiologymentioning

confidence: 95%

Section: Etiologymentioning

confidence: 99%

<p>Endomyocardial Fibrosis: Diagnosis and Management</p>

Khalil¹

2020

JVD

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“…Both acute and chronic phases of the disease are recognised [33]. Patients in the acute phase present with fever, itching, hives, dyspnoea, periorbital oedema and eosinophilia [34]. Patients with chronic EMF present with cachexia, stunted growth, hepatosplenomegaly and marked abdominal ascites with minimal peripheral oedema.…”

Section: Endomyocardial Fibrosismentioning

confidence: 99%

“…Patients with chronic EMF present with cachexia, stunted growth, hepatosplenomegaly and marked abdominal ascites with minimal peripheral oedema. In addition, digital clubbing, male feminisation and hypoalbuminaemia are common [34].…”

Section: Endomyocardial Fibrosismentioning

confidence: 99%

“…Endomyocardial fibrosis occurs in mainly three forms: biventricular involvement (55% of cases), followed by pure right ventricular and, rarely, pure left ventricular involvement [9]. The pathological hallmark of EMF is focal or diffuse endocardial thickening of the ventricular apices and/or the atrioventricular valves, seen as echo brightness of the endocardial surfaces, with resultant restrictive physiology and atrioventricular valve regurgitation [34]. Echocardiography may further reveal gross atrial dilatation, intramural or free thrombi, varying degrees of mitral and tricuspid regurgitation, retracted ventricles with cavity obliteration, evidence of secondary pulmonary hypertension, and sometimes large chronic pericardial effusions (Figure 4) [9,34].…”

Section: Endomyocardial Fibrosismentioning

confidence: 99%

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Echocardiography in Indigenous Populations and Resource Poor Settings

Marangou

Beaton

Aliku

et al. 2019

Heart, Lung and Circulation

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Cardiac Masses in a Patient With Pancreatic Adenocarcinoma and a History of Breast Carcinoma

2020

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A 64-year-old woman with borderline resectable pancreatic adenocarcinoma and a history of hormone receptor-positive left-sided breast cancer (treated with lumpectomy and radiation in 2014) was transferred to our hospital for management of a displaced percutaneous hepatobiliary drain. She was diagnosed as having pancreatic adenocarcinoma in September 2019 after developing right upper quadrant pain and jaundice, which prompted imaging and a subsequent endoscopic biopsy of a pancreatic head mass. She established oncologic care in Kentucky and received 1 dose of gemcitabine plus nanoparticle albuminbound (nab)-paclitaxel in early October 2019. Her posttreatment course was complicated by elevated levels of transaminases, significant fatigue, and an infusion port thrombosis. Her infusion port (right sided) was subsequently removed, and she was given 1.5 mg/kg of enoxaparin daily for anticoagulation.After her transfer, the oncology department was consulted regarding treatment options for her pancreatic cancer. Several hypodense lesions in the apex of her heart were appreciated on review of her previous chest computed tomography scan (Figure 1A). A subsequent transthoracic echocardiogram (Figure 1B) was obtained and revealed several discrete, partially mobile frondlike masses originating from her cardiac apex. The cardiology and cardiothoracic surgery departments were consulted for input pertaining to her case. Both services requested cardiac magnetic resonance imaging for further clarification of her imaging findings.

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Diagnosis and Management of Endomyocardial Fibrosis

Cited by 41 publications

References 75 publications

<p>Endomyocardial Fibrosis: Diagnosis and Management</p>

<p>Endomyocardial Fibrosis: Diagnosis and Management</p>

Echocardiography in Indigenous Populations and Resource Poor Settings

Cardiac Masses in a Patient With Pancreatic Adenocarcinoma and a History of Breast Carcinoma

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