Diabetic retinopathy in chronic pancreatitis

Natural Course of Chronic Pancreatitis

“…The only significant difference was the longer duration of diabetes in patients with retinopathy when compared with those without this complication. A longer observation time may explain the higher frequency of diabetic retinopathy in this study [88] as compared to the earlier investigations [85][86][87]. Similarly, Tiengo et al [89] and Couet et al [90] had found retinopathy in 31 and 41%, respectively, of patients with chronic pancreatitis.…”

“…Earlier investigations have shown that diabetic retinopathy is a rare complication of pancreatogenic diabetes with an occurrence rate of 7.4-18% [85][86][87]. Gullo et al [88] have shown that the risk of retinopathy and the characteristics of this complication in patients with chronic pancreatitis and secondary diabetes are the same as in patients with type I diabetes. About half of the patients studied in both groups had retinopathy; it was background, minimal, or mild-to-moderate without impairment of visual function.…”

Interactions between the Endocrine and Exocrine Pancreas and Their Clinical Relevance

“…The development of early microvascular complications in pancreatic DM is similar to that in other forms of DM. The prevalence and severity of diabetic retinopathy and neuropathy in pancreatic DM patients do not differ from those in patients with insulin-dependent DM, and depend on the duration of the DM and on the degree of adequacy of glycemic control [41,42] . The prevalence of complications in pancreatic DM was assessed in Japan by means of a questionnaire [13] .…”

Endocrine pancreatic insufficiency in chronic pancreatitis

“…However, comparison of the incidence of this complication in patients with type 1 diabetes with a group of CP patients indicated no difference in the risk for retinopathy in these two groups; the duration of known diabetes was on average 6.6 years, that is, similar to that in the fi rst group [55] . Neuropathy has been reported in about 30% of patients with CP and overt diabetes by electromyography [32] .…”