Diabetic Neuropathy among Type 2 Diabetes Mellitus Patients at Amplas Primary Health Care in Medan City

Amelia, Rina; Wahyuni, Arlinda Sari; Yunanda, Yuki

doi:10.3889/oamjms.2019.433

Cited by 22 publications

(24 citation statements)

References 14 publications

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“…In other reviews, the mean ages of the patients were between 50 and 60 years old [10,12]. This can be explained by the elevated diagnosis of diabetic neuropathy in the 51-60-year age group, in patients that have type 2 diabetes [51,52]. In addition, type 2 diabetes represents the greatest proportion of the total prevalence of diabetes (90%) and is characteristic of adult patients [53].…”

Section: Discussionmentioning

confidence: 96%

Exercise and Manual Therapy for Diabetic Peripheral Neuropathy: A Systematic Review

et al. 2021

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(1) Background: Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes mellitus (DM). Control of hyperglycaemia as well as surgical decompression are effective treatments for these patients. However, surgery is not indicated for all candidates. Manual therapy and physical exercise have been shown to be effective for peripheral neuropathies, and exercise for DM. The aim is to review the effectiveness of manual therapy and/or exercise in patients with DPN. (2) Methods: Randomised controlled clinical trials comparing the effects of manual therapy and/or exercise on pain, function and/or balance were selected. The search strategy was performed in PubMed, PEDro, Scopus, Cochrane and Web of Science databases. The PRISMA statement was followed. (3) Results: A total of 656 articles were registered, and 29 were selected. There was little consensus on DPN criteria selection. Aerobic, strength and balance exercises are beneficial for DPN. Sessions of 30–60 min, three times per week for 8 weeks seems to be the most used dose. Manual therapy is effective in the short term. A combination of both modalities was more beneficial than alone in one study. (4) Conclusions: Exercise and manual therapy are beneficial for patients with DPN. More studies should be carried out for analysing the potential effect of combining manual therapy and exercise.

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Section: Discussionmentioning

confidence: 96%

Exercise and Manual Therapy for Diabetic Peripheral Neuropathy: A Systematic Review

et al. 2021

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“…Hormonal differences in men and women affect the onset of neuropathy. High estrogen levels in women can interfere with the absorption of iodine, which plays a role in the formation of myelin nerves, while testosterone levels in men protect the body from T2DM, but not in women 24 . Gender is not the main determinant factor for complications of peripheral diabetic neuropathy because gender is only related to patients with hyperglycemia, but for hypercholesterolemia and hyperaggregation, there is no association.…”

Section: Discussionmentioning

confidence: 99%

The Impact Factors of Peripheral Diabetic Neuropathy Which is Along with Hyperglycemia, Hypercholesterolemia, and Hyperaggregation

Citra Amaniah Anhar,

Yetti Hernaningsih,

Puspa Wardhani, Soebagijo Adi

et al. 2021

Indian Journal of Forensic Medicine & Toxicology

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Objective: The prevalence of T2DM case in 2018 has increased by 10.9%. The majority of T2DM patients often ignore some of the most important conditions to experience complications, which is complications of PDN. This study aims to analyze the dominant factors in PDF patients with hyperglycemia, hypercholesterolemia, and hyperaggregation. Material and methods: This research is a case control study conducted from April to October 2020. The sample is 85 patients who have been confirmed to have PDN by neurologists aged 40 -65. Sampling was conducted at several hospitals in Surabaya with a purposive sampling method. Data analysis was conducted in three stages, namely univariate analysis, bivariate analysis and multivariate analysis. Results: 85 PDN patients who experienced hyperglycemia amounted to 81%, hypercholesterolemia 81%, and hyperaggregation 67%. The dominant factor affecting the three conditions (hyperglycemia, hypercholeterol, and hyperagregation) in this PDN patient was a history of hypertension with a value of p = {(0.012); (0.007); (0.001)} and also a long period of suffering from T2DM with p value = {(0.019); (0.025); (0.041)). Meanwhile, age, gender and regularity for treatment control were not the dominant influencing factors. Conclusion: Suffered for a long time from T2DM and a history of hypertension are the main determinants of peripheral diabetic neuropathy which is along by hyperglycemia, hypercholesterolemia, and hyperaggregation.

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“…3,6 In addition to its frequency, type 2 diabetes is further complicated by a number of comorbidities such as cardiovascular disorders, obesity, neuropathy, and nephropathy. [7][8][9][10] Moreover, cutaneous comorbidities are also common in patients with diabetes. About 79% of patients with either type 1 or 2 diabetes have at least one No changes in baseline TEWL.…”

Section: Introductionmentioning

confidence: 99%

“…The estimated occurrence of type 2 diabetes was 0.67 per 1000 subjects aged 10 to 19 years in the United States in 2017, 5 and living in rural areas and/or having a higher education level lowers the risk for type 2 diabetes 3,6 . In addition to its frequency, type 2 diabetes is further complicated by a number of comorbidities such as cardiovascular disorders, obesity, neuropathy, and nephropathy 7–10 . Moreover, cutaneous comorbidities are also common in patients with diabetes.…”

Section: Introductionmentioning

confidence: 99%

Alterations in epidermal function in type 2 diabetes: Implications for the management of this disease

Man

Wakefield

Mauro

et al. 2022

Journal of Diabetes

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Epidermal function is regulated by numerous exogenous and endogenous factors, including age, psychological stress, certain skin disorders, ultraviolet irradiation and pollution, and epidermal function itself can regulate cutaneous and extracutaneous functions. The biophysical properties of the stratum corneum reflect the status of both epidermal function and systemic conditions. Type 2 diabetes in both murine models and humans displays alterations in epidermal functions, including reduced levels of stratum corneum hydration and increased epidermal permeability as well as delayed permeability barrier recovery, which can all provoke and exacerbate cutaneous inflammation.Because inflammation plays a pathogenic role in type 2 diabetes, a therapy that improves epidermal functions could be an alternative approach to mitigating type 2 diabetes and its associated cutaneous disorders.

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Diabetic Neuropathy among Type 2 Diabetes Mellitus Patients at Amplas Primary Health Care in Medan City

Cited by 22 publications

References 14 publications

Exercise and Manual Therapy for Diabetic Peripheral Neuropathy: A Systematic Review

Exercise and Manual Therapy for Diabetic Peripheral Neuropathy: A Systematic Review

The Impact Factors of Peripheral Diabetic Neuropathy Which is Along with Hyperglycemia, Hypercholesterolemia, and Hyperaggregation

Alterations in epidermal function in type 2 diabetes: Implications for the management of this disease

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