“…The prevalence of diabetic renal disease is growing at an alarming rate worldwide and has imposed a high burden of disease-related morbidity and mortality in the recent decades (Huang et al, 2012;Jindal, Garcia-Touza, Jindal, Whaley-Connell, & Sowers, 2013;Reeves, Rawal, Abdel-Rahman, & Awad, 2012). Diabetic nephropathy shares many risk factors with cardiovascular disease (Luo et al, 2010;Sheen, Lin, Li, Bau, & Sheu, 2013), and usually occurs in conjunction with various metabolic abnormalities, such as hyperglycemia (Coresh, Astor, Greene, Eknoyan, & Levey, 2003;Ritz, 2008), dyslipidemia (Chawla et al, 2010;Lee et al, 2009), or overweight/obesity (Inker et al, 2014;Jindal et al, 2013); hypertension Haroun et al, 2003;Whelton, Perneger, He, & Klag, 1996); and smoking (Ritz, 2008).…”