“… 5 , 6 , 7 Interestingly, diabetes mellitus was reported to be a factor that independently affected liver stiffness after DAA treatment despite SVR. 8 The underlying mechanisms involving the presence of steatosis, especially before treatment, can be alcohol consumption, being overweight, obesity, diabetes type 2 mellitus, HCV genotype, Human Immunodeficiency Virus (HIV) coinfection, and genetic polymorphisms in genes, such as Transmembrane six Superfamily member 2 ( TM6SF2 ), Patatin-Like Phospholipase Domain Containing 3 ( PNPLA3 ) and Microsomal Triglyceride Transfer Protein ( MTTP ). 9 , 10 , 11 , 12 , 13 In this context, the role of host and viral characteristics associated with genetic polymorphisms in liver fat accumulation in chronic hepatitis C was investigated in the present study.…”