Effects of source/drain (S/D) doping density (N SD ) on the ballistic performance of III-V nanowire (NW) n-channel metal-oxide-semiconductor field-effect transistors (n-MOSFETs) are explored through atomistic quantum transport simulation. Different III-V materials (InAs, GaAs) and transport directions (<100>, <110>) are considered with Si included for benchmarking for a gate length of 13 nm. For III-V's, depending on the operating condition (OFF-current target for a given supply voltage), there exists an optimum N SD that maximizes ON-current (I ON ) by balancing source exhaustion versus tunneling leakage. For InAs, sub-threshold swing degrades significantly with increasing N SD due to the light effective mass (m*) and source-drain tunneling, so the optimum N SD is low. For GaAs, such dependence is much weaker due to the larger m*, and the optimum N SD is higher. With optimized N SD 's, InAs shows low ballistic I ON due to the low density-of-state (DOS) whereas GaAs NW with <110> transport direction shows good ballistic I ON due to the improved DOS with still high injection velocity, making it a better candidate for high performance device.INDEX TERMS III-V semiconductor materials, MOSFET, nanoscale devices, nanowires, semiconductor device modeling.