Development of the method of an electrohydrodynamic force effect on a boundary layer for active control of aerodynamic flows

Aleshin, B. S.; Khomich, V. Yu.; Chernyshev, S. L.

doi:10.1134/s1028335816120107

Cited by 11 publications

(1 citation statement)

References 4 publications

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“…Electrospun fiber has attracted increasing attention in localized chemotherapy because it appears as one of the most versatile and scalable drug carrier for local drug delivery . However, the encapsulated drugs close to the surface of electrospun fibers experience an initial burst release, which is extremely harmful for patients . Generally, bead‐on‐string fibers have been considered as by‐products in electrospinning process.…”

Section: Introductionmentioning

confidence: 99%

Knitted Silk Fibroin‐Reinforced Bead‐on‐String Electrospun Fibers for Sustained Drug Delivery Against Colon Cancer

Gou

Wang

et al. 2018

Macro Materials & Eng

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Bead‐on‐string electrospun fibers containing camptothecin (CPT) are fabricated on the surface of knitted silk fibroin (SF) meshes. Microscopic characterization reveals that the bead‐on‐string structure is prepared successfully and CPT is mainly located within the beaded structure. Interestingly, the CPT‐loaded beaded SF mesh (CPT‐SF mesh) has excellent mechanical properties. More importantly, it is able to perform a sustained CPT release without burst release. In vitro cytotoxicity tests further indicate that the CPT‐SF mesh shows much stronger anticolon cancer activity in comparison with SF meshes and beaded SF meshes. Hence, the CPT‐SF mesh has great potential as a promising local drug delivery system for colon cancer treatment.

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Section: Introductionmentioning

confidence: 99%