2017
DOI: 10.15171/jlms.2017.21
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Development of Temperature Distribution and Light Propagation Model in Biological Tissue Irradiated by 980 nm Laser Diode and Using COMSOL Simulation

Abstract: Introduction: The purpose of this project is to develop a mathematical model to investigate light distribution and study effective parameters such as laser power and irradiated time to get the optimal laser dosage to control hyperthermia. This study is expected to have a positive impact and a better simulation on laser treatment planning of biological tissues. Moreover, it may enable us to replace animal tests with the results of a COMSOL predictive model. Methods: We used in this work COMSOL5 model to simulat… Show more

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Cited by 11 publications
(9 citation statements)
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“…Shurrab et al developed a mathematical model of temperature distribution and light propagating in the tissue during laser‐induced hyperthermia to study the effective laser‐related parameters to control hyperthermia. They used COMSOL to simulate the light diffusion and bioheat equation in a mouse model as well as the effect of different parameters like power and irradiation exposure time on the tumor surrounding tissues with the aim of decreasing detrimental effects [277].…”
Section: Simulationsmentioning
confidence: 99%
“…Shurrab et al developed a mathematical model of temperature distribution and light propagating in the tissue during laser‐induced hyperthermia to study the effective laser‐related parameters to control hyperthermia. They used COMSOL to simulate the light diffusion and bioheat equation in a mouse model as well as the effect of different parameters like power and irradiation exposure time on the tumor surrounding tissues with the aim of decreasing detrimental effects [277].…”
Section: Simulationsmentioning
confidence: 99%
“…Several facts can explain the findings obtained in our study. The 980 nm diode laser used at the beginning of the treatment served as skin preparation and warm-up, which must have increased later the absorption of the serum [ 12 , 13 ]. The heating done by the 980 nm diode laser must have led to pore opening [ 12 , 13 ].…”
Section: Discussionmentioning
confidence: 99%
“…The 980 nm diode laser used at the beginning of the treatment served as skin preparation and warm-up, which must have increased later the absorption of the serum [ 12 , 13 ]. The heating done by the 980 nm diode laser must have led to pore opening [ 12 , 13 ]. Hence, the cream was able to penetrate deeper layers of the skin.…”
Section: Discussionmentioning
confidence: 99%
“…The remaining part is transferred to the surrounding tissue where it is heated. This creates the unwanted thermal effect in the neighboring tissues [6].…”
Section: Introductionmentioning
confidence: 99%