Development of sandwich electrochemiluminescence immunosensor for COVID-19 diagnosis by SARS-CoV-2 spike protein detection based on Au@BSA-luminol nanocomposites

Hosseini, Morteza; Sobhanie, Ebtesam; Salehnia, Foad; Xu, Guobao; Rabbani, Hodjattallah; Sheikholeslami, Mahsa N.; Firoozbakhtian, Ali; Sadeghi, Niloufar; Farajollah, Mohammad Hossein; Ganjali, Mohammad Reza; Vosough, Houman

doi:10.1016/j.bioelechem.2022.108161

Cited by 18 publications

(10 citation statements)

References 27 publications

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“…In a recent work by our team, we developed an ECL-based immunosensor for the detection of the virus [ 61 ]. Gold deposited GCEs were used as the working electrode.…”

Section: Ecl Biosensors For Viruses Detectionmentioning

confidence: 99%

Recent trends and advancements in electrochemiluminescence biosensors for human virus detection

Sobhanie¹,

Salehnia²,

Xu³

et al. 2022

TrAC Trends in Analytical Chemistry

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“…In a recent work by our team, we developed an ECL-based immunosensor for the detection of the virus [ 61 ]. Gold deposited GCEs were used as the working electrode.…”

Section: Ecl Biosensors For Viruses Detectionmentioning

confidence: 99%

Recent trends and advancements in electrochemiluminescence biosensors for human virus detection

Sobhanie¹,

Salehnia²,

Xu³

et al. 2022

TrAC Trends in Analytical Chemistry

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“…These methods are based on affinity reagents such as antibodies, aptamers, antibacterial peptides, and bacteriophages. Biosensors based on aptamers have received great attention in recent years because of their properties such as high binding affinity with long‐term stability and affordability [7–12] . Among the diagnostic methods, electrochemical‐based biosensors have features that make them very efficient in designing and manufacturing biosensors.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Aptasensor for Selective and Sensitive Detection of Staphylococcus aureus Using Graphene oxide/poly Deep Eutectic Solvent/Nickel Oxide Nanocomposite Modified Electrode

Rabiei,

Rezayan,

Hosseini

et al. 2024

ChemistrySelect

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Since that pathogenic bacteria are major threats to human health; this research describes the fabrication of an effective and sensitive platform based on graphene oxide/poly deep eutectic solvent/nickel oxide nano particles (GO/PDES/NiO NPs) nanocomposite at the surface of glassy carbon electrode for selective detection of Staphylococcus aureus (S. aureus). The DNA aptamers were immobilized on the modified electrode through the EDC/NHS chemistry. Each aptasensor modification step was checked by with cyclic voltammetry (CV) and electrochemical impedance spectra (EIS) techniques. The linear dynamic range of the proposed electrochemical aptasensor covered a large variation of S. aureus concentrations from 101 – 108 CFU.mL−1 and a detection limit of 10 CFU.mL−1 under optimum conditions was obtained. Analysis of spiked tap water, lake water and human serum samples revealed high potential of this aptasensor as a sensitive, effective, and label‐free promising tool for S. aureus detection. This is the first time that poly deep eutectic solvents used in live bacteria detection.

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“…Employing metal-based nanomaterials with a high surface-tovolume ratio can dramatically enhance the ECL signal intensity through an increase in the conductivity of the system. Various nanostructures of gold, [21,30] silver, [31,32] copper, [33,34] and iron complexes [35] have been reported as enhancers in the ECL of luminol systems.…”

Section: Introductionmentioning

confidence: 99%

Ti₃C₂/Ni/Sm‐Based Screen‐Printed‐Electrode for the ECL Detection of Hydrogen Peroxide as a Milk Preservative

Arshian,

Firoozbakhtian,

Salehnia

et al. 2024

ChemistrySelect

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Hydrogen peroxide is a widely used agent in the food industry for its sterilization, packaging, and transportation capabilities. However, its excessive concentration can lead to adverse health effects, especially in gastrointestinal conditions. As a result, it is crucial to detect its presence in food products, particularly milk. To address this need, we have developed a state‐of‐the‐art MXene‐based ECL system that can detect low‐concentration hydrogen peroxide levels with high sensitivity and accuracy. Our system incorporates 2D MXene structures, which not only enhance electrode conductivity but also form a complex with Ni/Sm‐LDH (layered double hydroxide) that enables detection across a broad linear range of 0.05–2 ppm in real samples. Furthermore, we have successfully lowered the detection limit to an impressive 0.005 ppm. With this innovative approach, we can ensure the safety and quality of food products, making it a significant breakthrough in the food industry.

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Development of sandwich electrochemiluminescence immunosensor for COVID-19 diagnosis by SARS-CoV-2 spike protein detection based on Au@BSA-luminol nanocomposites

Cited by 18 publications

References 27 publications

Recent trends and advancements in electrochemiluminescence biosensors for human virus detection

Recent trends and advancements in electrochemiluminescence biosensors for human virus detection

Electrochemical Aptasensor for Selective and Sensitive Detection of Staphylococcus aureus Using Graphene oxide/poly Deep Eutectic Solvent/Nickel Oxide Nanocomposite Modified Electrode

Ti₃C₂/Ni/Sm‐Based Screen‐Printed‐Electrode for the ECL Detection of Hydrogen Peroxide as a Milk Preservative

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Development of sandwich electrochemiluminescence immunosensor for COVID-19 diagnosis by SARS-CoV-2 spike protein detection based on Au@BSA-luminol nanocomposites

Cited by 18 publications

References 27 publications

Recent trends and advancements in electrochemiluminescence biosensors for human virus detection

Recent trends and advancements in electrochemiluminescence biosensors for human virus detection

Electrochemical Aptasensor for Selective and Sensitive Detection of Staphylococcus aureus Using Graphene oxide/poly Deep Eutectic Solvent/Nickel Oxide Nanocomposite Modified Electrode

Ti3C2/Ni/Sm‐Based Screen‐Printed‐Electrode for the ECL Detection of Hydrogen Peroxide as a Milk Preservative

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Ti₃C₂/Ni/Sm‐Based Screen‐Printed‐Electrode for the ECL Detection of Hydrogen Peroxide as a Milk Preservative