“…As a top-down technology, electrospinning is famous for its simplicity, efficiency and flexibility in direct preparation of nanofibers ( Du et al, 2022 ; Huang et al, 2022 ; Yao et al, 2022 ). At present, there are many researches using electrospinning as a tool to construct medicated nanofibers ( Huang et al, 2021 ; Peng et al, 2021 ; El-Shanshory et al, 2022 ; Hameed et al, 2022 ). These electrospun active nanofibers have been demonstrated to be useful for providing all kind of drug release profiles, such as pulsatile release, sustained release, delayed release, biphasic release, targeted release in a direct manner ( Sivan et al, 2022a ; Wang et al, 2022a ; Jiang et al, 2022b ; Liu et al, 2022b ; Wang et al, 2022b ; Zhao et al, 2022 ); and also for tissue engineering, wound dressing, and other regeneration medicines during the past two decades ( Zhang et al, 2021a ; Brimo et al, 2021 ; Zhao et al, 2021b ; Chen et al, 2022b ; Guo et al, 2022 ; Mosallanezhad et al, 2022 ; Shen et al, 2022 ; Sun et al, 2022 ).…”