Development of polyamide-6,6/chitosan electrospun hybrid nanofibrous scaffolds for tissue engineering application

Shrestha, Bishnu Kumar; Mousa, Hamouda M.; Tiwari, Arjun Prasad; Ko, Sung Won; Park, Chan Hee; Kim, Cheol Sang

doi:10.1016/j.carbpol.2016.03.094

Cited by 108 publications

(46 citation statements)

References 41 publications

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“…With good architecture, surface degradation and mechanical properties the nanofibrous scaffolds can be considered in bone tissue engineering applications . Electrospinning is the best technique for the fabrication of nanofibers from polymer solutions and provides nanofibers with the large surface area, porosity with controlled pore sizes and good degradability …”

Section: Introductionmentioning

confidence: 99%

“…[22][23][24] Electrospinning is the best technique for the fabrication of nanofibers from polymer solutions and provides nanofibers with the large surface area, porosity with controlled pore sizes and good degradability. [25][26][27][28] In the present study, the chemical modification was done on cylindrical Luffa by alkaline treatment using NaOH. The characterizations have been carried out to observe the difference in before and after alkaline treatment using Fouriertransform infrared spectroscopy (FTIR), X-ray powder diffraction (XRD), and scanning electron microscopy (SEM) respectively.…”

Section: Introductionmentioning

confidence: 99%

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Influence of chemically modified Luffa on the preparation of nanofiber and its biological evaluation for biomedical applications

Stella

Vijayalakshmi

2018

J Biomedical Materials Res

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In the present investigation, the natural cellulose was extracted from Luffa cylindrica vegetable sponge by chemical modification. Both chemically modified and unmodified Luffa was characterized by Fourier‐transform infrared spectroscopy (FTIR), X‐ray powder diffraction (XRD), scanning electron microscopy (SEM), and energy‐dispersive X‐ray spectroscopy. The chemically modified cellulose was used for the preparation of a nanofibrous scaffold using the electrospinning method. In order to achieve the uniform and bead free fibers with desired fiber diameter the parameters such as applied voltage, tip to collector distance, solution concentration were optimized. Different ratio of hydroxyapatite (HAP): polylactic acid (PLA) such as 40:60, 50:50, 60:40, and 70:30 have been selected for the current evaluation and was compared with HAP‐treated cellulose (TC)‐PLA. With the increase in the concentration of HAP in the polymeric network, the diameter of the fiber was found to be thin with the high electric field. The functional group, phase formation and dielectric and mechanical properties of the developed nanofiber have been characterized by FTIR, XRD, mechanical property measurements, and SEM. From the results, we observed that the polymer composite developed with the ratio of 70:30 produces a bead free product with enhanced mechanical and bioactivity property by the formation of hydroxy carbonated apatite layer on the surface. All the nanofibrous scaffold fabricated with and without modification have shown good Cyto compatibility on MG‐63 Osteoblast cell lines at 48 hr. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 107A: 610–620, 2019.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Influence of chemically modified Luffa on the preparation of nanofiber and its biological evaluation for biomedical applications

Stella

Vijayalakshmi

2018

J Biomedical Materials Res

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“…Many different approaches have been considered, for example, solar cells, fuel cells, and biodiesel, but each system has its own limitations [13][14][15]. Multifunctionality of the device is a requirement: it must have high specific strength and a high load-bearing capacity with minimal weight and volume fraction of the composite laminate [16,17]. Multifunctionality of the device is a requirement: it must have high specific strength and a high load-bearing capacity with minimal weight and volume fraction of the composite laminate [16,17].…”

Section: Introductionmentioning

confidence: 99%

“…A novel idea has been advanced to convert the entire automotive body into an energy storage device than could work in the absence of fuel and still support the required mechanical stresses. Multifunctionality of the device is a requirement: it must have high specific strength and a high load-bearing capacity with minimal weight and volume fraction of the composite laminate [16,17]. One strategy is to assemble several multifunctional structural laminates that together would provide significant improvements.…”

Section: Introductionmentioning

confidence: 99%

Recent development and challenges of multifunctional structural supercapacitors for automotive industries

Deka

Hazarika

Kim

et al. 2017

Int. J. Energy Res.

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Summary In the last decades, fuel scarcity and increasing pollution level pave the way for an extensive interest in alternatives to petroleum‐based fuels such as biodiesel, solar cells, lithium ion batteries, and supercapacitors. Among them, structural supercapacitors have been considered as promising candidates for automotive industries in present time. Herein, the use of carbon fiber‐based supercapacitors in automotive applications is reviewed. Carbon fiber is an excellent candidate for vehicle body applications, and its composites could be widely used in the development of supercapacitors that could provide both structural and energy storage functions. Different surface modification processes of the carbon fiber electrode to enhance the electrochemical as well as mechanical performances are discussed. The advantages of the glass fiber separator and its comparison with other types of dielectric media have been incorporated. The synthesis procedures of the multifunctional solid polymer electrolyte and its significance have been also elaborated. The fabrication process, component selection, limitations, and future challenges of these supercapacitors are briefly assimilated in this review. Copyright © 2017 John Wiley & Sons, Ltd.

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“…Pure chitosan nanofibers were produced from high molecular weight chitosan synthesized from Drosophila melanogaster [6]. Especially for tissue engineering, 3D core-shell scaffolds from polyamide-6,6 blended with chitosan [7] or from poly(epsilon-caprolactone) and chitosan were produced by coaxial electrospinning [8]. These fibers were also tested with respect to their antibacterial activity against E. coli and S. aureus [9].…”

Section: Introductionmentioning

confidence: 99%

Needleless Electrospinning of Pure and Blended Chitosan

Grimmelsmann

Homburg

Ehrmann

2017

IOP Conf. Ser.: Mater. Sci. Eng.

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Abstract:Chitosan is a biopolymer with bactericidal, fungicidal, hemostatic and other interesting properties. It can be used, e.g., in medical products, as a filter medium, in biotechnological purposes etc. For these possible applications, nanofiber mats with a large inner surface will be most efficient. This is why in a recent project, the electrospinning properties of pure chitosan as well as chitosan blended with poly(ethylene oxide) were investigated. Using a needleless nanospinning process, the technology under examination can be upscaled from lab to industrial scale, enabling direct transfer of the gained experiences to the intended application.

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Development of polyamide-6,6/chitosan electrospun hybrid nanofibrous scaffolds for tissue engineering application

Cited by 108 publications

References 41 publications

Influence of chemically modified Luffa on the preparation of nanofiber and its biological evaluation for biomedical applications

Influence of chemically modified Luffa on the preparation of nanofiber and its biological evaluation for biomedical applications

Recent development and challenges of multifunctional structural supercapacitors for automotive industries

Needleless Electrospinning of Pure and Blended Chitosan

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