Development of modified montmorillonite-bacterial cellulose nanocomposites as a novel substitute for burn skin and tissue regeneration

Sajjad, Wasim; Khan, Taous; Ul-Islam, Mazhar; Khan, Romana; Hussain, Zohaib; Khalid, Ayesha; Wahid, Fazli

doi:10.1016/j.carbpol.2018.11.023

Cited by 114 publications

(81 citation statements)

References 42 publications

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“…To ensure bone regeneration, polymers should be biocompatible, biodegradable, easily sterilized, adequate biomimetic properties (water content, optimal mechanical properties and porosity). Also, it has to provide suitable bioactivity to promote cell attachment and proliferation on the scaffold (Daugela et al 2018;Sajjad et al 2019).…”

Section: Hard Tissue Engineeringmentioning

confidence: 99%

Applications of bacterial-synthesized cellulose in veterinary medicine – a review

et al. 2019

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Tissue engineering promotes tissue regeneration through biomaterials that have excellent properties and have the potential to replace tissues. Many studies show that bacterial cellulose (BC) might ensure tissue regeneration and substitution, being used for the bioengineering of hard, cartilaginous and soft tissues. Bacterial cellulose is extensively used as wound dressing material and results show that BC is a promising tissue scaffold (bone, cardiovascular, urinary tissue). It can be combined with polymeric and non-polymeric compounds to acquire antimicrobial, cell-adhesion and proliferation properties. To ensure proper tissue regeneration, the material has to be: biocompatible, with minimum tissue reaction and biodegradability; bio-absorbable, to promote tissue development, cellular interaction and grow; resistant to support the weight of the newly formed tissue. Its versatile structure, physical and biochemical properties can be adjusted by adapting the bacteria culturing conditions. The main biomedical applications seem to be as hard (bone, dental), fibrocartilaginous (meniscal) and soft tissue (skin, cardiovascular, urinary) substituents. This paper reviews the current state of knowledge, challenges and future applications of BC and its biomedical potential in veterinary medicine. It was focused on the main uses in regeneration and scaffold tissue replacement and, although BC showed promising results, there is a lack of successful results of BC use in clinical practice. Most studies were performed only at experimental level and further research is needed for BC to enter clinical veterinary practice.

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Section: Hard Tissue Engineeringmentioning

confidence: 99%

Applications of bacterial-synthesized cellulose in veterinary medicine – a review

et al. 2019

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“…The release of Zn 2+ ions from the BC films was believed to the mechanism for the antibacterial activity which showed reduced growth of S. aureus and B. subtilis gram positive bacteria as well as E. coli and P. aeruginosa gram negative bacteria. As ion release can be a critical factor for producing antibacterial effect, BC composited have also been formed by immersion in suspensions of montmorillonite (a hydrous alumina-silicate clay) modified to containing Cu, Na, or Ca [137]. In this case, the zones of inhibition for the montmorillonite-BC composites with release of Cu were found to inhibit growth of E. coli and S. aureus, while release of Na inhibited MRSA, S. aureus, and E. coli, and the release of Ca inhibited E.coli, S. aureus, and C. fruendii.…”

Section: Biomedical Application Area Key Features Refmentioning

confidence: 99%

Engineering Bacterial Cellulose for Diverse Biomedical Applications

Sandhu¹,

Arpa²,

Chen³

et al. 2019

rpm

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Increasing interest in bacterial cellulose due to the huge potential which exists for the development of this new biomaterial for medical applications has been met with recent growth in research in engineering this unique microbial manufactured material. The mechanical properties, porosity, and biocompatibility of bacterial cellulose derived biomaterials are particularly attractive for use in wound healing, tissue engineering, and drug delivery applications. Advances in synthetic biology and soft materials engineering are pushing the value of this biomaterial to new levels. This review provides and in-depth discussion of these most recent approaches in processing as well as physical, chemical, and genetic modification of bacterial cellulose toward further improvement and expansion of its functionality. In addition, we provide specific attention to the marketed applications of the resulting engineered materials for medical research and conclude with prospective areas of consideration for expanding the clinical utility of this biomaterial to new directions.

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“…). The use of BNC as wound dressings is very widespread and popular on the market for medical applications . BNC also finds application in tissue engineering.…”

Section: Introductionmentioning

confidence: 99%

Bacterial nanocelullose in biomedical applications: a review

Sionkowska

Mężykowska

Piątek

2019

Polymer International

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This review reports recent advances in the application of bacterial nanocellulose (BNC) in biomedical fields. BNC has attracted both academic and industrial attention as it shows interesting properties for both biomedical and cosmetic applications. Herein, the structure, properties and selected applications of BNC in the preparation of wound dressings and artificial skin are discussed in general, and detailed examples are also drawn from the scientific literature. In this review the most common applications are presented in detail together with issues related to regenerative medicine and biomedicine, skin tissue engineering, auricular cartilage reconstruction, bone regeneration and the treatment of traumatic tympanic membrane perforation. © 2019 Society of Chemical Industry

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Development of modified montmorillonite-bacterial cellulose nanocomposites as a novel substitute for burn skin and tissue regeneration

Cited by 114 publications

References 42 publications

Applications of bacterial-synthesized cellulose in veterinary medicine – a review

Applications of bacterial-synthesized cellulose in veterinary medicine – a review

Engineering Bacterial Cellulose for Diverse Biomedical Applications

Bacterial nanocelullose in biomedical applications: a review

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