Development of Micro-Grippers for Tissue and Cell Manipulation with Direct Morphological Comparison

Cecchi, Rossana; Verotti, Matteo; Capata, Roberto; Dochshanov, Alden; Broggiato, G. B.; Crescenzi, Rocco; Balucani, M.; Natali, S.; Razzano, Giovanna; Lucchese, Franco; Bagolini, Alvise; Bellutti, P.; Sciubba, Enrico; Belfiore, Nicola Pio

doi:10.3390/mi6111451

Cited by 66 publications

(29 citation statements)

References 71 publications

(27 reference statements)

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“…The results obtained from the text analysis also showed an evident inclination of the students to the activities and practical work and therefore they confirmed the results obtained by using Gardner's inventory. Therefore, considering that the Course basic material is based on classical text books [18,19] and on some recent papers [20][21][22][23][24][25][26][27][28][29][30][31], i.e., written material, the peculiar above-mentioned results gave rise to the idea of encouraging our students to work in team (Interpersonal) and make use of handmade (Kinesthetic) models (Spatial-Visual).…”

Section: Resultsmentioning

confidence: 99%

Learning Micromanipulation, Part 1: An Approach Based on Multidimensional Ability Inventories and Text Mining

et al. 2018

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In the last decades, an effort has been made to improve the efficiency of high-level and academic education players. Nowadays, students’ preferences and habits are continuously evolving and so the educational institutions deal with important challenges, such as not losing attractiveness or preventing early abandonment during the programs. In many countries, some important universities are public, and so they receive national grants that are based on a variety of factors, on which the teaching efficiency has a great impact. This contribution presents a method to improve students commitment during traditional lessons and laboratory tests. The idea consists in planning some activities according to the students’ learning preferences, which were studied by means of two different approaches. The first one was based on Gardner’s multiple intelligence inventory, which is useful to highlight some peculiar characteristics of the students on the specific educational field. In the second method, direct interviews, voice recognition, and text mining were used to extract some interesting characteristics of the group of students who participated in the projects. The methods were applied in May 2018 to the students attending the course of Micro-Nano Sensors and Actuators for the postgraduate academic program dedicated to Industrial Nanotechnologies Engineering of the University of Rome La Sapienza. The present paper represents the first part of the investigation and it is dedicated essentially to the adopted methods. The second part of the work is presented in the companion paper dedicated to the presentation of the practical project that the students completed before the exam.

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Section: Resultsmentioning

confidence: 99%

Learning Micromanipulation, Part 1: An Approach Based on Multidimensional Ability Inventories and Text Mining

et al. 2018

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“…Besides, the ESA can also provide in-plane rotary output by curving the plate, which is widely applied in microgrippers [28][29][30][31]. In previous research, ESAs were generally integrated into the mechanical part to form a monolithic structure and then fabricated by chip manufacturing processes, e.g., silicon on insulator (SOI), low pressure chemical vapor deposition (LPCVD) [32][33][34][35], etc. Therefore, ESA is mostly used to drive a planar structure.…”

Section: Electrostatic Actuatormentioning

confidence: 99%

Survey on Recent Designs of Compliant Micro-/Nano-Positioning Stages

2018

Actuators

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Micromanipulation is a hot topic due to its enabling role in various research fields. In order to perform a high precision operation at a small scale, compliant mechanisms have been proposed and applied for decades. In microscale manipulation, micro-/nano-positioning is the most fundamental operation because a precision positioning is the premise of subsequent operations. This paper is concentrated on reviewing the state-of-the-art research on complaint micro-/nano-positioning stage design in recent years. It involves the major processes and components for designing a compliant positioning stage, e.g., actuator selection, stroke amplifier design, connecting scheme of the multi-DOF stage and structure optimization. The review provides a reference to design a compliant micro-/nano-positioning stage for pertinent applications.

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“…Relative motion among the pseudo-rigid parts i and j is possible because the thin cross-section of the curved element k behaves as a flexible rod. [15,64]).…”

Section: Stress Analysismentioning

confidence: 99%

Scalloping and Stress Concentration in DRIE-Manufactured Comb-Drives

et al. 2018

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In the last decades, microelectromechanical systems have been increasing their number of degrees of freedom and their structural complexity. Hence, most recently designed MEMSs have required higher mobility than in the past and higher structural strength and stability. In some applications, device thickness increased up to the order of tens (or hundred) of microns, which nowadays can be easily obtained by means of DRIE Bosch process. Unfortunately, scalloping introduces stress concentration regions in some parts of the structure. Stress concentration is a dangerous source of strength loss for the whole structure and for comb-drives actuators which may suffer from side pull-in. This paper presents an analytical approach to characterize stress concentrations in DRIE micro-machined MEMS. The method is based on the linear elasticity equations, the de Saint-Venant Principle, and the boundary value problem for the case of a torsional state of the beam. The results obtained by means of this theoretical method are then compared with those obtained by using two other methods: one based on finite difference discretization of the equations, and one based on finite element analysis (FEA). Finally, the new theoretical approach yields results which are in accordance with the known value of the stress concentration factor for asymptotically null radius notches.

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Development of Micro-Grippers for Tissue and Cell Manipulation with Direct Morphological Comparison

Cited by 66 publications

References 71 publications

Learning Micromanipulation, Part 1: An Approach Based on Multidimensional Ability Inventories and Text Mining

Learning Micromanipulation, Part 1: An Approach Based on Multidimensional Ability Inventories and Text Mining

Survey on Recent Designs of Compliant Micro-/Nano-Positioning Stages

Scalloping and Stress Concentration in DRIE-Manufactured Comb-Drives

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