Development of methodologies based on HPLC and Raman spectroscopy for monitoring the stability of lovastatin in solid state in the presence of gallic acid

Synergies of phenolic-acids’ surface-modified titanate nanotubes (TiNT) for enhanced photo-catalytic activities

“…2) showed reduced signals (3-4 orders of magnitude) of some bands or even their disappearance as well as appearance of several new bands within the range from 800 to 1800 cm À1 in comparison with the reference TiNTs where the characteristic bands of pure TiNTs are confirmed at 198 cm À1 , 273 cm À1 , 398 cm À1 , 512 cm À1 , and 638 cm À1 and within the range between 700 and 1000 cm À1 , as also observed by other authors [21][22][23][24], being generally attributed to the TiAO lattice vibrations during the anatase-phase TiO 2 . In order to obtain better insight in the characterizations of modified TiNTs in comparison with the non-modified ones, the Raman spectra of selected phenolic-acid molecules were characterized, being also in accordance with the references [25][26][27]. Several new bands that appeared within the Raman spectra of phenolic-modified TiNTs were, in general, characteristic of pure phenolic-acid derivatives being connected mainly with the aromatic ring vibrations, indicating the presence of phenolic acid on the TiNTs' surfaces.…”

Development and Validation of Liquid Chromatographic Method for the Simultaneous Estimation of Ezetimibe and Lovastatin in Human Plasma

“…Lovastatin is isolated from a Monascus and a strain of aspergillus terreus [14][15] . A number of analytical methods have already been published for the determination of Lovastatin in pharmaceutical formulations and in biological samples [16][17][18][19][20][21][22][23][24][25][26] . The combination therapy of ezetimibe with any statin is FDA approved and with this additional 12% to 21% absolute LDL cholesterol is reduced 27 .…”