Development of Matrix Metalloproteinases-Mediated Extracellular Matrix Remodeling in Regenerative Medicine: A Mini Review

Chen, Kaiqi; Xu, Mimi; Lu, Feng; He, Yunfan

doi:10.1007/s13770-023-00536-x

Tissue Eng Regen Med

2023

DOI: 10.1007/s13770-023-00536-x

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Development of Matrix Metalloproteinases-Mediated Extracellular Matrix Remodeling in Regenerative Medicine: A Mini Review

Kaiqi Chen

Mimi Xu

Feng Lu

et al.

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2024

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Cited by 4 publications

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“…The equilibrium between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) plays a crucial role in regulating the extent of connective tissue degradation and remodeling. The extracellular matrix (ECM) is a network of interconnected macromolecules that form a dynamic scaffold outside of the cells (18)(19)(20). Numerous studies have reported up-regulated expression of various MMP types in pterygium samples.…”

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confidence: 99%

Contribution of Matrix Metalloproteinase-2 Genotypes to Taiwan Pterygium Risk

HU,

HSIA,

WANG

et al. 2024

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Background/Aim: In the literature, the studies about the role of matrix metalloproteinase-2 (MMP-2) in pterygium diagnosis are mainly based on its protein expression. The role of MMP-2 variants has never been examined. The aim of this study was to examine the association of MMP-2 genotypes with pterygium risk. Materials and Methods: MMP-2 rs243865 and rs2285053 were genotyped in 140 pterygium cases and 280 nonpterygium controls by typical polymerase chain reactionrestriction fragment length polymorphism (PCR-RFLP) genotyping technology.

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mentioning

confidence: 99%

Contribution of Matrix Metalloproteinase-2 Genotypes to Taiwan Pterygium Risk

HU,

HSIA,

WANG

et al. 2024

In Vivo

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Cell-homing and immunomodulatory composite hydrogels for effective wound healing with neovascularization

Byun,

Han,

Kim

et al. 2024

Bioactive Materials

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Assessing Breast Cancer through Tumor Microenvironment Mapping of Collagen and Other Biomolecule Spectral Fingerprints─A Review

Chohan,

Biswas,

Wankhede

et al. 2024

ACS Sens.

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Breast cancer is a major challenge in the field of oncology, with around 2.3 million cases and around 670,000 deaths globally based on the GLOBOCAN 2022 data. Despite having advanced technologies, breast cancer remains the major type of cancer among women. This review highlights various collagen signatures and the role of different collagen types in breast tumor development, progression, and metastasis, along with the use of photoacoustic spectroscopy to offer insights into future cancer diagnostic applications without the need for surgery or other invasive techniques. Through mapping of the tumor microenvironment and spotlighting key components and their absorption wavelengths, we emphasize the need for extensive preclinical and clinical investigations.

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Development of Matrix Metalloproteinases-Mediated Extracellular Matrix Remodeling in Regenerative Medicine: A Mini Review

Cited by 4 publications

References 88 publications

Contribution of Matrix Metalloproteinase-2 Genotypes to Taiwan Pterygium Risk

Contribution of Matrix Metalloproteinase-2 Genotypes to Taiwan Pterygium Risk

Cell-homing and immunomodulatory composite hydrogels for effective wound healing with neovascularization

Assessing Breast Cancer through Tumor Microenvironment Mapping of Collagen and Other Biomolecule Spectral Fingerprints─A Review

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