Development of magnetic split-flow thin fractionation for continuous particle separation

Fuh, C. Bor; Tsai, Horng-Jyh; Lai, Jiunnren

doi:10.1016/j.aca.2003.08.034

Cited by 14 publications

(9 citation statements)

References 18 publications

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“…Several approaches have been suggested, including quadrupole magnetic field-flow fractionation [11] and split-flow thin (SPLITT) fractionation [12]. Magnetic separation techniques have recently gained attention due to their potential for integration into micro total analysis systems (mTAS) [3,[13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

The importance of particle type selection and temperature control for on-chip free-flow magnetophoresis

Tarn¹,

Peyman²,

Robert³

et al. 2009

Journal of Magnetism and Magnetic Materials

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Section: Introductionmentioning

confidence: 99%

The importance of particle type selection and temperature control for on-chip free-flow magnetophoresis

Tarn¹,

Peyman²,

Robert³

et al. 2009

Journal of Magnetism and Magnetic Materials

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“…Both dipole and quadrupole magnets have been utilised in SPLITT fractionation devices [17,[33][34][35][36][37][38][39]. The main applications have been biomedical analyses based on differences in the intrinsic and extrinsic magnetic properties of biological macromolecules.…”

Section: Splitt Fractionationmentioning

confidence: 99%

Particle Separation in Microfluidic Devices 3/4 SPLITT Fractionation and Microfluidics

Zhang¹,

Barber²,

Emerson³

2005

CAC

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In recent years, microfluidic devices have been increasingly used to separate particles such as colloids, macromolecules, cells, beads and droplets. Miniaturisation often introduces new functionalities and paradigms that are not possible at conventional macroscopic scales. In this paper, split-flow-thin fractionation techniques for particle separation are reviewed and the underlying physics of particle migration is discussed. The potential of these particle separation techniques in the design of integrated microfluidic systems is described. We then illustrate how numerical simulation can provide an increased understanding of the fluid-particle motion. The advantages of numerical simulation for rational design and operation of microfluidic devices are highlighted through two practical examples involving an ultrasonic cell washing system and a quadrupole magnetic flow sorter.

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“…Continuous immunomagnetic sorting of CD34+ progenitor cells was demonstrated with this system [7]. Other approaches take advantage of magnetic split-flow thin fractionation in a planar device or magnetic field-flow fractionation in a capillary channel [8][9][10].…”

Section: Introductionmentioning

confidence: 98%

Magnetic particle dosing and size separation in a microfluidic channel

Afshar

Moser

Lehnert

et al. 2011

Sensors and Actuators B: Chemical

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Development of magnetic split-flow thin fractionation for continuous particle separation

Cited by 14 publications

References 18 publications

The importance of particle type selection and temperature control for on-chip free-flow magnetophoresis

The importance of particle type selection and temperature control for on-chip free-flow magnetophoresis

Particle Separation in Microfluidic Devices 3/4 SPLITT Fractionation and Microfluidics

Magnetic particle dosing and size separation in a microfluidic channel

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