Development of invasive adenocarcinoma following colectomy with ileoanal anastomosis for familial polyposis coli

Hoehner, Jeff C.; Metcalf, Amanda M.

doi:10.1007/bf02050149

Cited by 87 publications

(45 citation statements)

References 18 publications

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“…Our review of the literature revealed seven cases of adenocarcinomas developing after restorative proctocolectomy with ileoanal anastomosis documented between 1984 and 1997 [27][28][29][30][31][32][33] (Table 4). Five of these patients were affected by UC, and two by FAP.…”

Section: Discussionmentioning

confidence: 99%

Functional outcome of stapled ileal pouch-anal canal anastomosis versus handsewn pouch-anal anastomosis

Saigusa

Kurahashi²,

Nakamura

et al. 2000

Surg Today

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This study was conducted to determine whether stapled ileal pouch-anal canal anastomosis (IACA) preserving the anal transitional zone (ATZ) or hand-sewn ileal pouch-anal anastomosis with mucosectomy (IPAA) is more beneficial in achieving disease eradication and better postoperative function. IACA was performed in 10 patients with ulcerative colitis (UC) and 10 patients with familial adenomatous polyposis (FAP), 15 of whom were examined proctoscopically. IPAA was performed in 4 patients with UC and 8 patients with FAP. The mean maximum resting pressure (MRP) was 55 mmHg in the IACA group and 34 mmHg in the IPAA group (P < 0.01). The anorectal inhibitory reflex was positive in 18 patients (90%) from the IACA group and 5 (42%) from the IPAA group (P < 0.05). The pre- and postoperative MRPs were 61 mmHg and 55 mmHg, respectively, in the IACA group vs 63 mmHg and 34 mmHg, respectively, in the IPAA group (P < 0.01). Whereas 16 (80%) of the 20 IACA patients could discriminate feces from gas, only 4 (33%) of the 12 IPAA patients could (P < 0.05). The mean observation period was 2.3 years, the mean length of the columnar cuff was 2.8 cm, and no case of dysplasia or adenoma was seen. Postoperative function is more favorable following IACA than following IPAA, both physiologically and symptomatically. However, long-term surveillance of the residual mucosa is necessary before making a final recommendation.

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Section: Discussionmentioning

confidence: 99%

Functional outcome of stapled ileal pouch-anal canal anastomosis versus handsewn pouch-anal anastomosis

Saigusa

Kurahashi²,

Nakamura

et al. 2000

Surg Today

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“…24 More recently, adenomas have been noted in the ileal pouch after RPC. [25][26][27][28][29] In this study we found that 35% of our patients had adenomas in their ileal pouch, an incidence similar to the 42% reported by Church et al 29 This risk is high considering the life expectancy of these patients.…”

Section: Discussionmentioning

confidence: 99%

Familial Adenomatous Polyposis: Prevalence of Adenomas in the Ileal Pouch After Restorative Proctocolectomy

Parc¹,

Olschwang²,

Desaint³

et al. 2001

Annals of Surgery

146

106

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“…There have already been three reported cases of cuff cancer in patients with FAP [9][10][11] . Regarding the anal transitional zone, two cancer cases have been reported [1] .…”

Section: Discussionmentioning

confidence: 99%

Development of Two Cancers in the Same Patient after Ileorectal and Ileal Pouch Anal Anastomosis for Familial Adenomatous Polyposis

Ulaş¹,

Neşşar²,

Bostanoğlu³

et al. 2005

Med Princ Pract

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Objective: To report a case of a patient with familial adenomatous polyposis. Clinical Presentation and Intervention: A 36-year-old male patient who suffered from rectal bleeding was treated with colectomy and ileorectal anastomosis for familial adenomatous polyposis (FAP) in 1974. After 19 years, in situ adenocarcinoma was detected in the rectal stump. Completion proctectomy, mucosectomy, and hand-sewn ileal pouch anal anastomosis with protective ileostomy were performed. In 2002, a metachronous cancer was detected at the anastomosis and abdominoperineal resection of the pouch and end ileostomy were performed. Later on, the perineum was excised locally because of cancer recurrence. Conclusion: This case shows that lifetime surveillance of the FAP patients after surgery is crucial.

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Development of invasive adenocarcinoma following colectomy with ileoanal anastomosis for familial polyposis coli

Abstract: We stress the need for lifelong proctoscopic surveillance in patients with familial polyposis coli treated by proctocolectomy with ileoanal anastomosis.

Cited by 87 publications

References 18 publications

Functional outcome of stapled ileal pouch-anal canal anastomosis versus handsewn pouch-anal anastomosis

Functional outcome of stapled ileal pouch-anal canal anastomosis versus handsewn pouch-anal anastomosis

Familial Adenomatous Polyposis: Prevalence of Adenomas in the Ileal Pouch After Restorative Proctocolectomy

Development of Two Cancers in the Same Patient after Ileorectal and Ileal Pouch Anal Anastomosis for Familial Adenomatous Polyposis

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