Development of indolealkylamine derivatives as potential multi-target agents for COVID-19 treatment

Spiroindole-containing compounds bearing phosphonate group of potential Mpro-SARS-CoV-2 inhibitory properties

“…2 ) [ 20 ]. 2-Substituted indolealkylamines were mentioned as potential anti-SARS-CoV-2 candidates with viral main protease (M pro ) inhibitory properties [ 21 ]. Many indole-containing compounds have also been mentioned by the in-silico studies as M pro inhibitory properties but lack of experimental bio-evidence has hindered their applicability [ 15 , [22] , [23] , [24] , [25] ].…”