Development of electrospun core–shell polymeric mat using poly (ethyl-2) cyanoacrylate/polyurethane to attenuate biological adhesion on polymeric mesh implants

Chalony, Carmen; Aguilar, Ludwig Erik; Kim, Ju Yeon; Kim, Cheol Sang

doi:10.1016/j.msec.2021.111930

Cited by 3 publications

(3 citation statements)

References 43 publications

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“…The as-designed mesh displayed excellent mechanical strength, biocompatibility, and collagen deposition, exhibiting good anti-hernia and anti-adhesion effects. One more adhesion-free composite material was reported by Chalony et al [72], who fabricated a biocompatible non-woven material from poly (ethyl-2) cyanoacrylate reinforced by polyurethane. The composite fibrous architecture demonstrated adequate mechanical properties for repairing the viscera layer if used as intraperitoneal hernia mesh implants.…”

Section: Other Innovative Materialsmentioning

confidence: 99%

A Review of Abdominal Meshes for Hernia Repair—Current Status and Emerging Solutions

Najm,

Niculescu,

Gaspar

et al. 2023

Materials

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Abdominal hernias are common issues in the clinical setting, burdening millions of patients worldwide. Associated with pain, decreased quality of life, and severe potential complications, abdominal wall hernias should be treated as soon as possible. Whether an open repair or laparoscopic surgical approach is tackled, mesh reinforcement is generally required to ensure a durable hernia repair. Over the years, numerous mesh products have been made available on the market and in clinical settings, yet each of the currently used meshes presents certain limitations that reflect on treatment outcomes. Thus, mesh development is still ongoing, and emerging solutions have reached various testing stages. In this regard, this paper aims to establish an up-to-date framework on abdominal meshes, briefly overviewing currently available solutions for hernia repair and discussing in detail the most recent advances in the field. Particularly, there are presented the developments in lightweight materials, meshes with improved attachment, antimicrobial fabrics, composite and hybrid textiles, and performant mesh designs, followed by a systematic review of recently completed clinical trials.

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Section: Other Innovative Materialsmentioning

confidence: 99%

A Review of Abdominal Meshes for Hernia Repair—Current Status and Emerging Solutions

Najm,

Niculescu,

Gaspar

et al. 2023

Materials

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“…Electrospinning acts as an efficient smart platform in a wide range of regenerative tissue applications (tendon, cartilage, cardiovascular, neural, skin, and bone regeneration) as the potential solution to current biomaterial (such as hydrogels) limitations. Coaxial electrospinning [ 318 ], direct blending [ 319 ], emulsion electrospinning [ 320 ], and surface modification [ 321 ] are the most common two-dimensional or 3D tissue engineering scaffold fabrication methods. Since most electrospinning materials are hydrophobic and lack bioactive sites for cell recognition and adhesion, fiber functionalization is sometimes necessary for electrospun fibers to be applied in regenerative medicine [ 322 , 323 ].…”

Section: Smart Engineered Materials For Abdominal Herniamentioning

confidence: 99%

Abdominal wall hernia repair: from prosthetic meshes to smart materials

Saiding,

Chen,

Wang

et al. 2023

Materials Today Bio

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“…Chalony and colleagues [ 114 ] focused their research on creating an adhesion-free, biocompatible, nonwoven material. In this respect, they used poly (ethyl-2) cyanoacrylate reinforced by polyurethane core to generate an electrospun composite mat.…”

Section: Materials Optimization Strategiesmentioning

confidence: 99%

Novel Material Optimization Strategies for Developing Upgraded Abdominal Meshes

Najm,

Niculescu,

Rădulescu

et al. 2023

IJMS

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Over 20 million hernias are operated on globally per year, with most interventions requiring mesh reinforcement. A wide range of such medical devices are currently available on the market, most fabricated from synthetic polymers. Yet, searching for an ideal mesh is an ongoing process, with continuous efforts directed toward developing upgraded implants by modifying existing products or creating innovative systems from scratch. In this regard, this review presents the most frequently employed polymers for mesh fabrication, outlining the market available products and their relevant characteristics, further focusing on the state-of-the-art mesh approaches. Specifically, we mainly discuss recent studies concerning coating application, nanomaterials addition, stem cell seeding, and 3D printing of custom mesh designs.

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Development of electrospun core–shell polymeric mat using poly (ethyl-2) cyanoacrylate/polyurethane to attenuate biological adhesion on polymeric mesh implants

Cited by 3 publications

References 43 publications

A Review of Abdominal Meshes for Hernia Repair—Current Status and Emerging Solutions

A Review of Abdominal Meshes for Hernia Repair—Current Status and Emerging Solutions

Abdominal wall hernia repair: from prosthetic meshes to smart materials

Novel Material Optimization Strategies for Developing Upgraded Abdominal Meshes

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