Development of calcium release mechanisms during starfish oocyte maturation

Chiba, Kazuyoshi; Kado, R. T.; Jaffe, Laurinda A.

doi:10.1016/0012-1606(90)90080-3

Cited by 135 publications

(98 citation statements)

References 41 publications

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“…3 in Immature and Mature Oocytes-The amount of InsP 3 necessary to release the same amount of Ca 2ϩ in mature starfish oocytes is 20-to 50-fold lower than in immature oocytes. The sensitivity of InsP 3 receptors evidently increases during the maturation process (17). It has been recently shown that the increased response to InsP 3 was not linked to the up-regulation and/or to the redistribution of the receptors in starfish oocytes (18).…”

Section: Photolysis Of Caged Insp 3 During Maturation and Ca 2ϩmentioning

confidence: 98%

“…In starfish oocytes, InsP 3 has been shown to release signifi- cantly more Ca 2ϩ at the end of the maturation process (17). The effect could be traced back to: (a) the increase in the amount of Ca 2ϩ trapped in the ER as shown in mouse oocytes (36); (b) the increase in the expression and/or redistribution of the InsP 3 receptors during the maturation process as previously described in Xenopus and mouse oocytes (36,37); and (c) changes in the InsP 3 receptors that increase their response to InsP 3 .…”

Section: Modulation Of the Actin Cytoskeleton By Mpf Is Responsible Fmentioning

confidence: 99%

“…The initial activation of MPF in Asterina pectinifera, however, has been suggested to occur in the cytoplasm via the Akt (protein kinase B)-dependent inactivation of Myt1 (a member of Wee1 family) that phosphorylates CDK1 on Thr-14 and Tyr-15 (16). The response of Ca 2ϩ stores to InsP 3 has been shown to increase during oocyte maturation, so that more calcium is released when InsP 3 is injected into a mature oocyte (17). This is not due to either redistribution or an increase in the expression of InsP 3 receptors (18).…”

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confidence: 99%

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The M-phase-promoting Factor Modulates the Sensitivity of the Ca2+ Stores to Inositol 1,4,5-Trisphosphate via the Actin Cytoskeleton

Lim

Ercolano

Kyozuka³

et al. 2003

Journal of Biological Chemistry

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The resumption of the meiotic cycle (maturation) induced by 1-methyladenine in prophase-arrested starfish oocytes is indicated by the breakdown of the germinal vesicle and is characterized by the increased sensitivity of the Ca 2؉ stores to inositol 1,4,5-trisphosphate (InsP 3 ) to InsP 3 starting at the animal hemisphere (where the germinal vesicle was originally located) and propagating along the animal/vegetal axis of the oocyte. This initiates Ca 2؉ signals around the germinal vesicle before nuclear envelope breakdown. Previous studies have suggested that the final activation of the maturation-promoting factor (MPF), a cyclin-dependent kinase, which is the major element controlling the entry of eukaryotic cells into the M phase, occurs in the nucleus. MPF is then exported to the cytoplasm where its activity is autocatalytically amplified following a similar animal/vegetal spatial pattern. We have investigated whether activated MPF was involved in the increased sensitivity of the Ca 2؉ response to InsP 3 . We have found that the development of increased sensitivity of the Ca 2؉ stores to InsP 3 receptors together with the Ca 2؉ signals in the perinuclear region was blocked in oocytes treated with the specific MPF inhibitor roscovitine. That the nuclear MPF activation is indeed required for changes of the InsP 3 receptors sensitivity was shown by enucleating or by dissecting oocytes into vegetal and animal hemispheres prior to the addition of 1-MA. MPF activity 50 min after 1-methyladenine addition was much lower in the enucleated oocytes and in the vegetal hemisphere, which did not contain the germinal vesicle, as compared with the animal hemisphere, which did contain it. The Ca 2؉ increase induced by InsP 3 under these experimental conditions correlated with the changes in actin cytoskeleton induced by MPF.

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Section: Photolysis Of Caged Insp 3 During Maturation and Ca 2ϩmentioning

confidence: 98%

Section: Modulation Of the Actin Cytoskeleton By Mpf Is Responsible Fmentioning

confidence: 99%

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confidence: 99%

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The M-phase-promoting Factor Modulates the Sensitivity of the Ca2+ Stores to Inositol 1,4,5-Trisphosphate via the Actin Cytoskeleton

Lim

Ercolano

Kyozuka³

et al. 2003

Journal of Biological Chemistry

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“…An increase in the sensitivity of IP 3 -dependent Ca 2þ release during oocyte maturation is a hallmark of Ca 2þ signaling differentiation in many species, including starfish (Chiba et al, 1990), hamster (Fujiwara et al, 1993), mouse (Jones et al, 1994;Mehlmann and Kline, 1994), and Xenopus (Terasaki et al, 2001;Machaca, 2004). However, the mechanisms underlying this enhanced Ca 2þ release are vaguely defined in the literature.…”

Section: Physiological Roles Of Ca 2r At Fertilizationmentioning

confidence: 99%

Ca²⁺ signaling differentiation during oocyte maturation

Machaca

2007

Journal Cellular Physiology

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Oocyte maturation is an essential cellular differentiation pathway that prepares the egg for activation at fertilization leading to the initiation of embryogenesis. An integral attribute of oocyte maturation is the remodeling of Ca 2þ signaling pathways endowing the egg with the capacity to produce a specialized Ca 2þ transient at fertilization that is necessary and sufficient for egg activation. Consequently, mechanistic elucidation of Ca 2þ signaling differentiation during oocyte maturation is fundamental to our understanding of egg activation, and offers a glimpse into Ca 2þ signaling regulation during the cell cycle.

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“…The appearance of cortical ER-rich domains during maturation correlates with an increase in Journal of Cell Science 115 (18) sensitivity to Ins(1,4,5)P3 and to sperm-induced Ca 2+ release (Chiba et al, 1990;Shiraishi et al, 1995;Mehlmann and Kline, 1994;Terasaki et al, 2001) (reviewed in Sardet et al, 2002). Local injections of Ins(1,4,5)P3 and sperm extracts in mouse eggs have revealed that the egg cortex is a region of higher sensitivity to Ins(1,4,5)P3 and to sperm extracts (Oda et al, 1999).…”

Section: Ca 2+ Wave Pacemakers In Eggs Reside In Cortical Errich Domainsmentioning

confidence: 99%

Calcium wave pacemakers in eggs

Dumollard

Carroll

Dupont

et al. 2002

Journal of Cell Science

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During the past 25 years, the characterization of sperm-triggered calcium signals in eggs has progressed from the discovery of a single calcium increase at fertilization in the medaka fish to the observation of repetitive calcium waves initiated by multiple meiotic calcium wave pacemakers in the ascidian. In eggs of all animal species, sperm-triggered inositol (1,4,5)-trisphosphate[Ins(1,4,5)P3] production regulates the vast array of calcium wave patterns observed in the different species. The spatial organization of calcium waves is driven either by the intracellular distribution of the calcium release machinery or by the localized and dynamic production of calcium-releasing second messengers. In the highly polarized egg cell, cortical endoplasmic reticulum (ER)-rich clusters act as pacemaker sites dedicated to the initiation of global calcium waves. The extensive ER network made of interconnected ER-rich domains supports calcium wave propagation throughout the egg. Fertilization triggers two types of calcium wave pacemakers depending on the species: in mice, the pacemaker site in the vegetal cortex of the egg is probably a site that has enhanced sensitivity to Ins(1,4,5)P3; in ascidians, the calcium wave pacemaker may rely on a local source of Ins(1,4,5)P3 production apposed to a cluster of ER in the vegetal cortex.

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Development of calcium release mechanisms during starfish oocyte maturation

Cited by 135 publications

References 41 publications

The M-phase-promoting Factor Modulates the Sensitivity of the Ca2+ Stores to Inositol 1,4,5-Trisphosphate via the Actin Cytoskeleton

The M-phase-promoting Factor Modulates the Sensitivity of the Ca2+ Stores to Inositol 1,4,5-Trisphosphate via the Actin Cytoskeleton

Ca²⁺ signaling differentiation during oocyte maturation

Calcium wave pacemakers in eggs

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Development of calcium release mechanisms during starfish oocyte maturation

Cited by 135 publications

References 41 publications

The M-phase-promoting Factor Modulates the Sensitivity of the Ca2+ Stores to Inositol 1,4,5-Trisphosphate via the Actin Cytoskeleton

The M-phase-promoting Factor Modulates the Sensitivity of the Ca2+ Stores to Inositol 1,4,5-Trisphosphate via the Actin Cytoskeleton

Ca2+ signaling differentiation during oocyte maturation

Calcium wave pacemakers in eggs

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Ca²⁺ signaling differentiation during oocyte maturation