Development of biocompatible and corrosion-resistant plasma electrolytic oxidation coating over zinc for orthopedic implant applications

Structural and temporal dynamics analysis of zinc-based biomaterials: History, research hotspots and emerging trends

“…The enhanced proliferation of endothelial cells (ECs) is expected to promote re-endothelialization within the scaffold, preventing in-stent restenosis and neointimal hyperplasia [ 127 , 128 ]. Various methods have been employed for coating preparation, including the immersion transformation method [ 129 , 130 ], hydrothermal method [ 131 ], plasma electrolytic oxidation (PEO) [ [132] , [133] , [134] , [135] , [136] ], phosphate chemical conversion method (PCC) [ 120 , 137 ], anodic oxidation (AD) [ 138 ], magnetron sputtering technique [ 139 ], electrophoretic deposition (EPD) [ 125 , 126 ], atomic layer deposition [ 140 ], ultrasonic spray coating [ 141 ], sol-gel method [ 142 ], dip coating method [ 124 ], etc.…”

Fucoidan- and Ciprofloxacin-Doped Plasma-Activated Polymer Coatings on Biodegradable Zinc: Hemocompatibility and Drug Release

“…Materials originating from natural or synthetic sources that are developed for use in medical applications to interact with biological systems and replace, repair, or enhance their function are called biomaterials. − Common types of biomaterials are prepared from metals, ceramics, polymers, and composites. − A new group of materials, biodegradable metals (BMs), that are designed to degrade in vivo over a selected time is currently being developed. − BMs are materials that are supposed to degrade by natural biological processes to substances that are well tolerated by the host environment. These materials must be made from biocompatible elemental metals such as magnesium, iron, and zinc, and their alloys or composites. − Among them, zinc is considered to be the most promising due to its beneficial health effects connected to bone healing, wide processing possibilities due to the low melting point, and tunable corrosion rate . Degradable metallic implants can complement the frequently used inert metallic materials and be useful in specific applications in which the presence of the implant in the body over a long time is unnecessary.…”

“… 12 − 16 Among them, zinc is considered to be the most promising due to its beneficial health effects connected to bone healing, wide processing possibilities due to the low melting point, and tunable corrosion rate. 17 Degradable metallic implants can complement the frequently used inert metallic materials and be useful in specific applications in which the presence of the implant in the body over a long time is unnecessary. This will eliminate the need for a second surgery to remove the implant after fulfilling its mission, which reduces the risk of implant rejection and even provides the release of beneficial substances participating in the bone tissue regeneration process (e.g., zinc ions).…”

Unveiling the Effect of Particle Incorporation in PEO Coatings on the Corrosion and Wear Performance of Magnesium Implants

“…In other words, the particle shapes and sizes have not changed significantly. Another possibility is reactivity or a slight reactivity of the incorporation [39,40]. Because of high-energy discharges in the PEO process and reactions with other matrix and electrolyte elements, this condition may result in the melting of particles [41].…”