Development of Arginine Based Monopeptides as Cationic Surfactants from Pure Amino Acid

Abstract

A mino acid-based surfactants constitute a class of cationic surfactants with excellent surface p roperties, wide biological activ ity, low potential to xicity. Essential structural factors for their antimicrobial activity include both the length of the fatty residue and the presence of the protonated guanidine function. These features and the use of natural raw materials such as Arginine and fatty acids for their synthesis, make them interesting candidates as preservatives and antiseptics in pharmaceutical, food and cosmetic fo rmulat ions. The present work describes the synthesis (at lab scale), the physicochemical properties of long chain N α -acyl arginine ethyl esters with a chain of 8 and 9 carbon atoms. These compounds have been prepared by condensation of L-arg inine ethyl ester dihydrochloride with corresponding acyl chlorides in the presence of base. The basic charastristic properties such as physical appearance, structural identificat ion by IR/ H 1 NMR, water solubility at different pH and surface tension studies of the synthesized co mpounds are discussed. The Antimicrobial properties of the co mpounds of invention are studied by determin ing their M inimu m inhibitory concentration for different microorganisms.

Cationic Gemini Surfactant as a Corrosion Inhibitor and a Biocide for High Salinity Sulfidogenic Bacteria Originating from an Oil‐Field Water Tank

“…The biocidal effect of the synthesized surfactants against the environmental sulfidogenic-bacteria was evaluated by determine the minimum inhibitory concentration (MIC). The MIC is defined as the lowest concentration of antimicrobial agent that inhibits the development of visible microorganism growth [20]. Samples were taken from the bulk phase of reactor A after 5 days cultivation and tested for viable bacterial counts using the most probable number (MPN) method [21].…”

Thermodynamics of Ion-Exchange Reaction in Predicting the Ionic Selectivity of Auchlite ARA-9366 and Auchlite A-378 Anion Exchange Resins

“…The exchange capacity of ion exchange resins was experimentally determined by the standard method [17] using sodium nitrate and titrating against standard silver nitrate solution. Ion exchange resins (0.500 g) in chloride form were equilibrated with iodide ion solution of different concentrations at a constant temperature of 30.0 °C for 3 h. From the results of kinetics study reported earlier [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36]; it was observed that this duration was adequate to attain the ion exchange equilibrium. After 3 h, the iodide ion solutions in equilibrium with ion exchange resins in chloride form were analyzed for their chloride and iodide ion concentrations by …”

Thermodynamics of Ion-Exchange Reaction in Predicting the Ionic Selectivity of Auchlite ARA-9366 and Auchlite A-378 Anion Exchange Resins

“…The exchange capacity of ion exchange resins was experimentally determined by the standard method [17] using sodium nitrate and titrating against standard silver nitrate solution. Ion exchange resins (0.500 g) in chloride form were equilibrated with iodide ion solution of different concentrations at a constant temperature of 30.0 °C for 3 h. From the results of kinetics study reported earlier [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36]; it was observed that this duration was adequate to attain the ion exchange equilibrium. After 3 h, the iodide ion solutions in equilibrium with ion exchange resins in chloride form were analyzed for their chloride and iodide ion concentrations by…”