ABSTRACT. This paper presents the synthesis and antimicrobial studies of Palladium (II) complexes of ThioSemicarbazone Pd(L 1 H) 2 Cl 2 and Semicarbazone Pd(L 2 H) 2 Cl 2 derived from 5-Bromo Isatin. All complexes reported here had been characterised by 1 H NMR and IR spectral studies .the complexes are diamagnetic in nature and showing square planner geometry. The IR spectral data reveals that both the Schiff's bases behave as bidentate ligands and are co-ordinated to Pd (II) metal through the sulfur and hydrogenic nitrogen atom. All the new synthesized compounds were screened for antibacterial activity against four of the test organisms like Bacillus pumilus, Micrococcus Lutes, E.coli, Salmonella abony.
The thermodynamic approach was applied to predict the trend selectivity of industrial grade anion exchange resin Auchlite A-378 in chloride form towards iodide and bromide ions in the solution. The study was conducted by performing the Clˉ/Iˉ and Clˉ/Brˉ uni-univalent ion exchange reactions under gradually increasing temperature conditions. The thermodynamic equilibrium constants K values were used to calculate the enthalpies of the two uni-univalent ion exchange reactions. It was observed that the K values for Clˉ/Iˉ ion exchange reaction were higher than Clˉ/Brˉ exchange reaction under identical experimental conditions. Also the enthalpy values for the two uniunivalent ion exchange reactions were calculated as -39.51 and -18.38 kJ/mol respectively. The high K and low enthalpy values obtained for Clˉ/Iˉ ion exchange reaction is responsible for higher selectivity of the resin towards iodide ions as compared to that towards bromide ions, when both the ions are present in the same solution.
This paper presents the synthesis and antimicrobial studies of Palladium (II) complexes of ThioSemicarbazone Pd (L1H)2Cl2 and Semicarbazone Pd (L2H)2Cl2 derived from 5-Bromo Isatin. All complexes reported here had been characterised by1H NMR and IR spectral studies .the complexes are diamagnetic in nature and showing square planner geometry. The IR spectral data reveals that both the Schiff’s bases behave as bidentate ligands and are co-ordinated to Pd (II) metal through the sulfur and hydrogenic nitrogen atom. All the new synthesized compounds were screened for antibacterial activity against four of the test organisms like Bacillus pumilus, Micrococcus Lutes, E.coli, Salmonella abony.
The selectivity behaviour of nuclear grade anion exchange resin Auchlite ARA-9366 in chloride form towards iodide and bromide ions in the solution was studied. The trend in selectivity of the resin was predicted on the basis of thermodynamics of Clˉ/Iˉ and Clˉ/Brˉ uni-univalent ion exchange reactions. It was observed that the equilibrium constants K values for Clˉ/Iˉ ion exchange reaction were higher than that calculated for Clˉ/Brˉ exchange under identical experimental conditions. Also the enthalpy values for the two uni-univalent ion exchange reactions were calculated as -47.87 and -36.14 kJ/mol respectively. The high K and low enthalpy values obtained for Clˉ/Iˉ ion exchange reaction as compared to that obtained during Clˉ/Brˉ exchange supports higher selectivity of the resin towards iodide ions as compared to that towards bromide ions, when both the ions are present in the same solution.
The research article represents the extraction of Embelin from its plant source and synthesis, characterisation, lipid lowering activities and antibacterial studies of some Benzoyl ester substituted derivatives of Embelin. The derivatives of Embelin, EL -1 to EL -5 were prepared by treating Embelin with Meta and Para substituted benzoyl chloride in presence of base pyridine and dichloromethane. Benzoyl ester substituted derivatives of Embelin molecule also shows more or less medicinal properties then the parent Embelin molecule. The synthesized compound were characterised and identified on the basis of elemental analysis, UV, FTIR, Mass and NMR spectroscopy and their antibacterial activities were studied against test organism viz B. subtilis gram positive, S.aureus Gram positive, C.Albicans Antifungal and E.coli Gram negative. The lipid lowering activities of prepared compound were also studied in percentage on pancreatic lipase inhibition simply on the basis of change in international unit (IU).
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