Development of an ultrasound-enhanced smartphone colorimetric biosensor for ultrasensitive hydrogen peroxide detection and its applications

Abstract

In this work, we developed the first ultrasound technique enhanced smartphone application for highly sensitive determination of hydrogen peroxide (H2O2).

A Portable Reflective Absorbance Spectrophotometric Smartphone Device for the Rapid and Highly Accurate Determination of Amlodipine in Pharmaceutical Formulation and Human Urine Samples

“…The comparison of analytical performance obtained by this proposed method and other methods using spectrophotometric techniques was showed in Table 1. 15,24,[39][40][41][42][43][44][45][46][47] Altogether, our proposed method exhibited a wide linearity range and the lowest detection limit for the quantitative analysis of amlodipine comparing with the other methods without the difficult sample preparation method such as the extraction step and heat pretreatment step. Furthermore, the proposed technique can be portable to on-site measurement so that it can be considered as a simple, fast and convenient method for point of care analysis and industries routine.…”

“…Nowadays, the spectrophotometric method can be performed by using smartphone systems to reduce expensive cost, easy to use because their operating system is the smallest and portable. [20][21][22][23][24] As well, its camera lenses are high-quality hardware to evaluate colorimetric or light intensity via Complementary Metal Oxide Semiconductor (CMOS). 25,26 For instance, M. Á. Aguirre et al, developed the smartphone application for ibuprofen analysis in commercial tablets.…”

Architecture of a multi-channel and easy-to-make microfluidic paper-based colorimetric device (μPCD) towards selective and sensitive recognition of uric acid by AuNPs: an innovative portable tool for the rapid and low-cost identification of clinically relevant biomolecules

“…24 In recent years, several colorimetric biosensors have designed for UA detection. 23,[25][26][27] Recently, the integration of advanced biosensors on microuidic substrates has received much attention. 28 Microuidics system is made up of channels with the size of tens to hundreds of micrometers that can analyze small amounts of liquids.…”

Efficient Assay for the Detection of Hydrogen Peroxide by Estimating Enzyme Promiscuous Activity in the Perhydrolysis Reaction

“…[2] Besides, its oxidant properties are widely applied in the pharmaceutical and biochemical industries. [3] H 2 O 2 is also known as the major species among reactive oxygen species (ROS), produced by cell mitochondria [4] and has been emerged as an indispensable messenger of cellular signaling cascades. [5] However, the presence of hydrogen peroxide influences the activity of certain enzymes.…”

“…H 2 O 2 has comparatively mild reactivity and is believed to play a meaningful role in the reversible oxidation in biological systems [2] . Besides, its oxidant properties are widely applied in the pharmaceutical and biochemical industries [3] . H 2 O 2 is also known as the major species among reactive oxygen species (ROS), produced by cell mitochondria [4] and has been emerged as an indispensable messenger of cellular signaling cascades [5] .…”