Development of Alcohol Dehydrogenase and Aldehyde Dehydrogenases in the Offspring of Female Rats Chronically Treated with Ethanol

Abstract

The influence of maternal ethanol drinking on the development of alcohol dehydrogenase and aldehyde dehydrogenases in the liver of the offspring was studied in Wistar rats. No statistically significant differences were found between the ethanol group and the control group. Ke.v-words:Aldehyde dehydrogenase-alcohol dehydrogenase -development-maternal ethanol drinking-rats.Ethanol is metabolized in the liver mainly by the enzymes alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). There are at least two different ALDH's in the rat liver (Tottmar el a/. 1973). ALDH I is located in the mitochondrion