Development of a next day functioning measure to assess the impact of sleep disturbance due to restless legs syndrome: The restless legs syndrome-next day impact questionnaire

Co-Morbidity, Mortality, Quality of Life and the Healthcare/Welfare/Social Costs of Disordered Sleep: A Rapid Review

“…Cognitive impairment, reduced alertness, poor emotional adaptation, excessive drowsiness, social problems, etc. are also reportedly related to RLS [74,75]. Sleep deprivation also increases irritability and hyperactivity.…”

Can A Nursing Intervention Improve the Sleep Pattern Disorders in Patients Undergoing Hemodialysis in Morning and Afternoon Shifts?

“…This has been shown by the improvement of their scores in these factors throughout the intervention, and by the multivariate analysis which identified the independent effect of these factors on the PSQI score. In congruence with this finding regarding the effect of psychosocial factors on sleep, Lasch [31] mentioned that the physical, mental, emotional and social health may impair sleep in ESRD patients. However, other factors to be considered are the treatment-related factors, abnormalities in melatonin, alteration in thermoregulatory mechanisms, and co-morbidities [1,11].…”

A pilot study to evaluate simulated driving performance and cognitive function in healthy subjects and patients with restless legs syndrome

“…Dr Chen is currently an employee of XenoPort, Inc.; Dr Shaw has no financial connection to XenoPort, Inc.; Dr Canafax is a former employee of XenoPort, Inc.; Dr Ware is a consultant to XenoPort, Inc. lack of energy, sleepiness, and cognitive deficit, such as difficulty concentrating, feeling forgetful, and less alert. 26 Thus, the lack of effect of RLS on the AM simulated driving as measured by mean LPV was not expected. Additionally, no worsening of mean LPVs by epoch or after a 40-minute drive was observed in subjects with RLS, a phenomenon that was typically seen in sleep-deprived and obstructive sleep apnea (OSA) patients.…”