Development of a fluorescence immunoassay for highly sensitive detection of amantadine using the nanoassembly of carbon dots and MnO2 nanosheets as the signal probe

A Perspective on Application of Carbon Quantum Dots in Luminescence Immunoassays

“…The sensitivity and selectivity of immunoassay measurements based on CQD luminescence signals, and the importance of residual harmful chemicals detection in food chemistry have encouraged Shen and co-workers to expand CQD application in the food industry (Dong et al, 2019b ). In their study, the luminescence signal recovery was employed as a detection signal for amantadine (AMD).…”

“… (A) Synthesis and (B) fabrication of designed luminescence immunoassay to detect amantadine (AMD). Panels reproduced from Dong et al ( 2019b ). Copyright 2019, Elsevier.…”

An ultrasensitive colorimetric and fluorescence dual-readout assay for glutathione with a carbon dot–MnO2 nanosheet platform based on the inner filter effect

“…As a class of two-dimensional transition metal dioxides, manganese dioxide (MnO 2 ) nanosheets, have been applied in many elds including energy generation, photocatalysis, sensing, and photothermal therapy, due to its outstanding properties including large specic surface area, fast electron transfer rate, and strong light absorption capability with wide wavelength range. [28][29][30] In recent years, MnO 2 nanosheets have been used as uorescence quenchers to constructed bio-/ chemical sensing platforms on the basis of uorescence resonance energy transfer (FRET). 31 C-dots and MnO 2 nanosheets have been reported as assay platform through the formation of C-dots-MnO 2 nanocomposites, in which MnO 2 nanosheets can be transformed to Mn 2+ by reductive molecules through the redox reaction.…”

Eco-Friendly Fluorescent ELISA Based on Bifunctional Phage for Ultrasensitive Detection of Ochratoxin A in Corn

“…The utilization of fluorescent signals as replacements of colorimetric signals is a simple and promising method to increase the sensitivity of ELISA [14,15]. Highly sensitive fluorescent immunoassays involving various fluorescent compounds, including organic dyes, upconverting nanoparticles (UCNPs) and quantum dots (QDs) have been developed.…”