Development and validation of the functional assessment of cancer therapy nasopharyngeal cancer subscale

Tong, Michael C. F.; Lo, Phoebe S.Y.; Wong, Ka Hing; Yeung, Richie; Hasselt, C. Andrew van; Eremenco, Sonya; Cella, David

doi:10.1002/hed.21023

Cited by 30 publications

(45 citation statements)

References 31 publications

(21 reference statements)

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“…Other studies that tested the reproducibility of the FACT-G questionnaire and their specific modules confirm the results of the present study [25,33-37]. …”

Section: Discussionsupporting

confidence: 90%

Evaluation of the Psychometric Properties of the Functional Assessment of Cancer Therapy-Cervix Questionnaire in Brazil

Fregnani

Latorre

et al. 2013

PLoS ONE

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BackgroundAlthough cervical cancer is the second most common tumor among Brazilian women, studies that evaluate the quality of life of these women are still scarce. This situation is explained by the lack of specific and validated tools for this purpose in Portuguese (Brazil). The aim of this study was to evaluate the psychometric properties of the Portuguese version of the FACT-CX (Functional Assessment of Cancer Therapy-Cervix) questionnaire in a population of Brazilian women with cervical cancer.MethodsThe psychometric properties of the FACT-CX questionnaire were tested in a sample of 100 women diagnosed with cervical cancer who were previously treated in the Barretos Cancer Hospital. We analyzed the internal consistency (Cronbach's alpha), reproducibility (intraclass correlation coefficient - ICC), confirmatory factor analysis, convergent validity (correlation with the SF-36 questionnaire), and discriminant validity by disease stage and two questions related to self-perception of health was also performed.ResultsThe scales had Cronbach´s alpha coefficients ranging from 0.61 to 0.80. However, three scales did not have a statistically significant coefficient greater than 0.70. The ICC ranged from 0.68 to 0.82 and all considered satisfactory. Factor analysis did not generate consistent components. The FACT-G and FACT-CX total scores had good internal consistency and reproducibility, and also correlated well with the General Health and Vitality scales of the SF-36. However, only two FACT-CX scales had a significant correlation with SF-36. Discriminant analysis showed that FACT-CX failed to discriminate groups according to clinical stage but was able to divide the women according to the self-perception of health.ConclusionFATC-CX total score had good internal consistency, reproducibility and discriminant validity. In addition, it correlated well with General Health and Vitality scales of SF-36. However, three scales had questionable internal consistency and only two had significant correlation with SF-36.

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“…Other studies that tested the reproducibility of the FACT-G questionnaire and their specific modules confirm the results of the present study [25,33-37]. …”

Section: Discussionsupporting

confidence: 90%

Evaluation of the Psychometric Properties of the Functional Assessment of Cancer Therapy-Cervix Questionnaire in Brazil

Fregnani

Latorre

et al. 2013

PLoS ONE

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“…A lower Cronbach α value also may occur with scales that contain a question coded in the opposite direction from other questions in the scale (for instance, “I am satisfied with how I am coping with my illness”). This may be the case with the EWB subscale, which, in some other studies, has resulted in intermittently lower internal consistency than other subscales 9, 28, 29. Finally, a low Cronbach α also can occur in disease‐free patients who do not endorse cancer‐specific concerns, such as disease progression and anxiety related to death.…”

Section: Discussionmentioning

confidence: 95%

Prospective evaluation of the reliability, validity, and minimally important difference of the functional assessment of cancer therapy‐gastric (FACT‐Ga) quality‐of‐life instrument

Garland

Pelletier

Lawe

et al. 2010

Cancer

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BACKGROUND:Recently, the Functional Assessment of Cancer Therapy-Gastric (FACT-Ga) was developed to measure the quality of life (QoL) of patients with gastric cancer. This newly developed instrument has not yet been validated. METHODS: Eighty-two patients with gastric adenocarcinoma completed questionnaires at baseline. The FACTGa scores were measured as a function of disease stage and performance status, and they were correlated with the Medical Outcomes Study 36-item short-form health survey (SF-36), the Beck Depression Inventory-II, the MarlowCrowne Social Desirability Scale, the Paulhus Deception Scale, and the State-Trait Anxiety Inventory. Patients received a second questionnaire 2 weeks after baseline to evaluate test-retest reliability and again at 3 months to evaluate the sensitivity of the FACT-Ga to changes in performance status and to estimate the minimally important differences in scores that represented meaningful change. RESULTS: The internal and test-retest reliability of the FACT-Ga instrument was adequate. With the exception of the social well being subscale, all FACT-Ga scores were correlated as hypothesized with other measures. Relevant components of the FACT-Ga were sensitive to changes in performance status. CONCLUSIONS: The current results indicated that the FACT-Ga provides a valid and reliable measurement of QoL in patients with gastric adenocarcinoma. It is a useful instrument for QoL assessment in clinical trials, and it also may be useful for the detection of significant changes in the QoL of individual patients.

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“…A few studies used the EORTC QLQ-C30 questionnaire and the EORTC QLQ-H&N35 questionnaire [10–13]. Some studies used the Functional Assessment of Cancer Therapy-General (FACT-G) scale, the Functional Assessment of Cancer Therapy-Head and Neck (FACT-H&N) module [14, 15], and the Functional Assessment of Cancer Therapy-Nasopharyngeal (FACT-NP) subscale [16]. Other studies used the MOS 36-item short-form health survey (SF-36) [17, 18] and the University of Washington Quality of Life Questionnaire [19].…”

Section: Discussionmentioning

confidence: 99%

Concurrent chemoradiotherapy degrades the quality of life of patients with stage II nasopharyngeal carcinoma as compared to radiotherapy

et al. 2017

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The purpose of this study was to compare the quality of life (QoL) of stage II nasopharyngeal carcinoma (NPC) patients treated with radiotherapy (RT) versus concurrent chemoradiotherapy (CCRT). In a cross-sectional study, these patients were treated with RT (n = 55) or CCRT (n = 51) between June 2008 and June 2013. For all subjects, disease-free survival was more than 3 years. QoL was assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) questions and the Head and Neck 35 (EORTC QLQ-H&N35) questions. RT had better outcomes than CCRT for global QoL, functional scales, symptom scales of fatigue and insomnia, financial problems, and weight gain. Survivors receiving 1 cycle of concurrent chemotherapy had worse QoL outcomes than survivors receiving 2 cycles of concurrent chemotherapy. Patients receiving 3 cycles of concurrent chemotherapy had the best QoL outcomes. Thus, CCRT adversely affects the QoL of patients with stage II NPC as compared to radiotherapy.

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Development and validation of the functional assessment of cancer therapy nasopharyngeal cancer subscale

Abstract: The FACT-NP is a reliable and valid instrument for measuring QOL in patients with NPC.

Cited by 30 publications

References 31 publications

Evaluation of the Psychometric Properties of the Functional Assessment of Cancer Therapy-Cervix Questionnaire in Brazil

Evaluation of the Psychometric Properties of the Functional Assessment of Cancer Therapy-Cervix Questionnaire in Brazil

Prospective evaluation of the reliability, validity, and minimally important difference of the functional assessment of cancer therapy‐gastric (FACT‐Ga) quality‐of‐life instrument

Concurrent chemoradiotherapy degrades the quality of life of patients with stage II nasopharyngeal carcinoma as compared to radiotherapy

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