Development and validation of a quantification method for α-humulene and trans-caryophyllene in Cordia verbenacea by high performance liquid chromatography

Gomes, Márcio Vinícius; Silva, J.D. da; Ribeiro, Ana Ferreira; Cabral, Lúcio Mendes; Sousa, Valéria Pereira de

doi:10.1016/j.bjp.2019.01.009

Cited by 16 publications

(9 citation statements)

References 24 publications

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“…Mass spectrometric (MS) fingerprints also can be developed. Chromatographic fingerprints can be obtained using Thin-layer chromatography (TLC) [ 77 ], High-performance thin-layer chromatography (HPTLC) [ 18 ], High performance liquid chromatography (HPLC) [ 17 ], Ultra-high performance liquid chromatography (UHPLC) [ 105 ], Capillary electrophoresis (CE) [ 29 ], Gas chromatography (GC) [ 64 ], Gas chromatography-mass spectrometry (GC–MS) [ 61 ], Two-dimensional gas chromatography-time-of-flight mass spectrometry (GCxGC-TOFMS) [ 63 ].…”

Section: Authentication Of Plant-derived Moleculesmentioning

confidence: 99%

Plant-derived natural products for drug discovery: current approaches and prospects

Nasim

Sandeep

Mohanty

2022

Nucleus

111

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Nature has abundant source of drugs that need to be identified/purified for use as essential biologics, either individually or in combination in the modern medical field. These drugs are divided into small bio-molecules, plant-made biologics, and a recently introduced third category known as phytopharmaceutical drugs. The development of phytopharmaceutical medicines is based on the ethnopharmacological approach, which relies on the traditional medicine system. The concept of ‘one-disease one-target drug’ is becoming less popular, and the use of plant extracts, fractions, and molecules is the new paradigm that holds promising scope to formulate appropriate drugs. This led to discovering a new concept known as polypharmacology, where natural products from varying sources can engage with multiple human physiology targets. This article summarizes different approaches for phytopharmaceutical drug development and discusses the progress in systems biology and computational tools for identifying drug targets. We review the existing drug delivery methods to facilitate the efficient delivery of drugs to the targets. In addition, we describe different analytical techniques for the authentication and fingerprinting of plant materials. Finally, we highlight the role of biopharming in developing plant-based biologics.

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Section: Authentication Of Plant-derived Moleculesmentioning

confidence: 99%

Plant-derived natural products for drug discovery: current approaches and prospects

Nasim

Sandeep

Mohanty

2022

Nucleus

111

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“…The LC-HRMS/MS data were processed in the Thermo Xcalibur software v3, and compound annotation was performed by comparing the MS and MS/MS data to those available in public databases (MassBank of North America, https://mona.fiehnlab.ucdavis.edu/) and based on chemical structures of compounds previously isolated from Pterodon species. [28] , [29] , [30] In addition, CAR content presented in SO was quantified by HPLC from previously described assay [31] .…”

Section: Methodsmentioning

confidence: 99%

“…The separation was carried out at 34 °C on a C18-RP LiChroCART® (150 mm × 4.0 mm, 5 µm particle size) and guard (5 mm × 4.0 mm, 4 µm) columns (Merck). The isocratic mobile phase was composed of a mixture of acetonitrile: water (70:30 v/v) at a constant flow rate of 1.2 mL/min as previously reported [31] . The injection volume was 10 µL for all standards and samples.…”

Section: Methodsmentioning

confidence: 99%

Lecithin-based nanocapsule loading sucupira (Pterodon emarginatus) oil effects in experimental mucositis

Miceli

Andrade²,

Carvalho³

et al. 2022

Toxicology Reports

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“…Most studies have addressed the biological activity and/or phytoconstituents identification of Cordia essential oil. Sixty-three articles were selected, but five dealing with essential oil of Cordia did not have enough information on biological activity, phytochemicals, and plant drugs used in the extraction process: pharmacokinetics and tissue distribution of phytoconstituents of essential oil (Chaves et al, 2008); methodology for quantifying C. curassavica in raw materials and pharmaceutical formulations (Gomes et al, 2019); histopathological, immunohistochemical and biochemical of essential oil topical application (Perini et al, 2015); clinical evaluation of the efficacy and safety of the use of C. curassavica essential oil (Refsio et al, 2005); release…”

Section: Study Characteristicsmentioning

confidence: 99%

Essential oils of Cordia species, compounds and applications: a systematic review

Andrade¹,

Martins²,

Barros³

et al. 2022

BLACPMA

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The purpose of this systematic review was to identify the available literature on the essential oil from species of genus Cordia. This study followed the Preferred Reporting Items for Systematic Reviews. The search was conducted on four databases: LILACS, PubMed, Science Direct, and Scopus until June 5th, 2020, with no time or language restrictions. Sixty out of the 1,333 initially gathered studies fit the inclusion criteria after the selection process. Nine species of Cordiawere reported in the selected studies, out of which 79% of the evaluated studies reported essential oil from Cordia curassavica. The essential oil extraction methods identified were hydrodistillation and steam distillation. As for biological application, antimicrobial, anti-inflammatory, larvicidal and antioxidant activities were the most reported. The main compounds reported for essential oil were β-caryophyllene, α-humulene, α-pinene, bicyclogermacrene, and sabinene. The information reported in this systematic review can contribute scientifically to the recognition of the importance of the genus Cordia.

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Development and validation of a quantification method for α-humulene and trans-caryophyllene in Cordia verbenacea by high performance liquid chromatography

Cited by 16 publications

References 24 publications

Plant-derived natural products for drug discovery: current approaches and prospects

Plant-derived natural products for drug discovery: current approaches and prospects

Lecithin-based nanocapsule loading sucupira (Pterodon emarginatus) oil effects in experimental mucositis

Essential oils of Cordia species, compounds and applications: a systematic review

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