Development and evaluation of a visual aid using see-through display for patients with retinitis pigmentosa

Ikeda, Yasuhiro; Suzuki, Eiji; Kuramata, Takashi; Kozaki, Tetsuo; Koyama, Tetsuya; Kato, Yukio; Murakami, Yusuke; Enaida, Hiroshi; Ishibashi, Tatsuro

doi:10.1007/s10384-014-0354-0

Cited by 15 publications

(19 citation statements)

References 12 publications

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“…It is estimated that 2.0 million individuals are affected with RP worldwide [ 1 ]. Although much effort has been made in developing new treatments, there is no effective treatment for RP [ 2 – 8 ]. Because RP is a progressive disease and can lead to severe visual impairments, it can lead to severe psychological distress.…”

Section: Introductionmentioning

confidence: 99%

Quantitative analyses of factors related to anxiety and depression in patients with retinitis pigmentosa

et al. 2018

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The purpose of this study is to determine the factors related to anxiety and depression in patients with retinitis pigmentosa (RP). The status of anxiety and depression was determined in RP patients with the Hospital Anxiety and Depression Scale (HADS) questionnaire which consisted of subscales for HADS-anxiety (HADS-A) and HADS-depression (HADS-D). The vision-specific quality of life (VSQOL) was assessed with the National Eye Institute Visual Function Questionnaire 25 (NEI-VFQ25). The correlations between the HADS-A or HADS-D scores and vision-related clinical parameters such as the best-corrected visual acuity (BCVA), Functional Acuity Score, Functional Field Score, Functional Vision Score, the NEI- VFQ25 subscale score were determined. The socioeconomic status, such as the work status and membership in the RP society, was investigated to determine the factors related to the HADS-A and HADS-D scores. One hundred and twelve RP patients (46 men and 66 women) with mean age of 60.7±15.4 (standard deviation) years were studied. The HADS-A score was not significantly correlated with any visual functions but was significantly correlated with the general health condition (r = -0.34, P<0.001) and the role limitation (r = -0.20, P = 0.03) of the NEI-VFQ25 subscale. The HADS-D score was significantly correlated with all the visual functions (r = -0.38 to 0.29, P<0.001), the NEI-VFQ25 subscale score (r = - 0.58 to -0.33, P<0.001) by Spearman’s correlations. The HADS-A score was significantly higher in the members of the RP society than in non-members (P = 0.013). The mean HADS-D score of employed individuals was significantly lower than that of unemployed ones (P = 0.001) by the Mann-Whitney U test. The results indicate that visual function impairments and vision-related quality of life are associated with a depressive state, and the general health condition is related to anxiety in RP patients. Being employed may be strongly correlated with the degree of depression in RP patients.

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Section: Introductionmentioning

confidence: 99%

Quantitative analyses of factors related to anxiety and depression in patients with retinitis pigmentosa

et al. 2018

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“…Only 10 of the studies reviewed involved a quantitative assessment of mobility performance and of these, 8 of them [45][46][47][48][52][53][54]77 recorded a significant reduction in efficiency with vision enhancement. Of the other two studies, which observed similar or better efficiency, in both of them, 68,76 the mobility courses were relatively simple with large walkable areas and a small number of relatively large obstacles. Therefore, currently, there is no good evidence that vision enhancements using HMDs improve walking efficiency.…”

Section: Discussionmentioning

confidence: 77%

“… 54 Conversely, using four times minified black and white image overlays, another study observed a significant reduction in the number of collisions without a reduction in walking speed in eight people with PFL and night-blindness caused by RP compared to the performance without the HMD. 68 This study did not provide clinical information about the participants, and the apparent contradiction could result from differences in participants or differences in the complexity of the experimental environments.…”

Section: Resultsmentioning

confidence: 92%

“…That is, they used large, high-contrast obstacles, large walkable areas, and did not include surface level changes, light level changes, or dynamically moving obstacles and stairs. 46 – 48 , 53 , 68 Therefore, it is difficult to understand how the results might apply in real-world situations. Another limitation of the existing literature is the failure to compare mobility performance with HMDs with that achieved using the person's usual mobility aids.…”

Section: Discussionmentioning

confidence: 99%

“…Expanding VF size is potentially useful as it is an important predictor of mobility performance. [13][14][15] Eight studies, 54,[66][67][68][69][70][71][72] summarized in Appendix Table A2, assessed the effects of minification on orientation and mobility.…”

Section: Minificationmentioning

confidence: 99%

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Ability of Head-Mounted Display Technology to Improve Mobility in People With Low Vision: A Systematic Review

Htike

Margrain

Lai

et al. 2020

Trans. Vis. Sci. Tech.

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The purpose of this study was to undertake a systematic literature review on how vision enhancements, implemented using head-mounted displays (HMDs), can improve mobility, orientation, and associated aspects of visual function in people with low vision. Methods: The databases Medline, Chinl, Scopus, and Web of Science were searched for potentially relevant studies. Publications from all years until November 2018 were identified based on predefined inclusion and exclusion criteria. The data were tabulated and synthesized to produce a systematic review. Results: The search identified 28 relevant papers describing the performance of vision enhancement techniques on mobility and associated visual tasks. Simplifying visual scenes improved obstacle detection and object recognition but decreased walking speed. Minification techniques increased the size of the visual field by 3 to 5 times and improved visual search performance. However, the impact of minification on mobility has not been studied extensively. Clinical trials with commercially available devices recorded poor results relative to conventional aids. Conclusions: The effects of current vision enhancements using HMDs are mixed. They appear to reduce mobility efficiency but improved obstacle detection and object recognition. The review highlights the lack of controlled studies with robust study designs. To support the evidence base, well-designed trials with larger sample sizes that represent different types of impairments and real-life scenarios are required. Future work should focus on identifying the needs of people with different types of vision impairment and providing targeted enhancements. Translational Relevance: This literature review examines the evidence regarding the ability of HMD technology to improve mobility in people with sight loss.

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Night-vision aid using see-through display for patients with retinitis pigmentosa

et al. 2019

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Development and evaluation of a visual aid using see-through display for patients with retinitis pigmentosa

Abstract: This device enabled the subjects to see objects that could not be recognized by the unaided eye. Our visual aid effectively assisted RP patients with night blindness.

Cited by 15 publications

References 12 publications

Quantitative analyses of factors related to anxiety and depression in patients with retinitis pigmentosa

Quantitative analyses of factors related to anxiety and depression in patients with retinitis pigmentosa

Ability of Head-Mounted Display Technology to Improve Mobility in People With Low Vision: A Systematic Review

Night-vision aid using see-through display for patients with retinitis pigmentosa

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