Detrended-Fluctuation-Analysis (DFA) and High-Frequency-Oscillation (HFO) Coefficients and Their Relationship to Epileptic Seizures

Abstract

We tested the applicability of methods based on Detrended Fluctuation Analysis and HFO detection to the analysis of EEG signals from patients diagnosed with epilepsy, in order to test how efficient these methods would behave in a seizure prediction application. We were able to statistically distinguish the coefficients estimated in the pre-ictal period from the coefficients obtained on the inter-ictal period, suggesting that the methods can be used to the development of seizure detection algorithms.