Diamond multi electrode arrays (MEAs) and ultra-micro electrode array (uMEA) fabricated from boron-doped nanocrystalline (BNCD) thin-films, show excellent performances when detecting cell activity in both amperometric and potentiometric applications. Furthermore they are suitable for delivering electrical stimulation to elicit bioelectric events. Results obtained with our previous 9-channels uMEA for single cells at high spatial resolution, and 16channels MEA for multicellular samples, validated the signal quality of diamond MEAs in comparison with competing technologies. The latest progresses are reported in this paper were we describe a new generation of devices with enhanced performances: a 12-channel uMEA for recordings from a single cell at high spatial resolution, and a 64-channel MEA to accommodate larger multicellular samples. The technology is based on a 200 mm thin high-temperature glass with the same thermal expansion coefficient of silicon and a spin-on seeding method. Preliminary experiments show excellent electrodes activity and a strongly improved transparency.
This paper proposes a new method for carrying out joint blind equalization and blind estimation of the bit-error-rate (BER) in the output of baud-rate FIR equalizers. A simple test for assessing decision errors in the output of the decision device is derived. A comparative study of several BER estimator methods is presented in terms of convergence rate and tracking capability of both static and dynamic channels. Simulations not only validate theoretical results but also point out the effectiveness of the new proposition in terms of low computational burden and accurate BER estimation. Finally, an application of the new proposition for the detection and correction of misconvergence due to local minima issues is also presented.
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