Determining Water Content in Human Nails with a Portable Near-Infrared Spectrometer

Egawa, Mariko; Fukuhara, Tadao; Takahashi, Masanori; Ozaki, Yukihiro

doi:10.1366/00037020360626032

Cited by 34 publications

(35 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Egawa et al (2003) investigated its potential to determine the water content of human nail plates. Spectra were collected from 108 cut nail plates from the free edge of the nail tip from the fingernails of 17 healthy volunteers (22-60 years, mean 41.3; 8 males, 9 females).…”

Section: Near Infrared-diffuse Reflectance (Nir-dr) Spectroscopymentioning

confidence: 99%

The human nail – Barrier characterisation and permeation enhancement

Walters¹,

Abdalghafor

Lane

2012

International Journal of Pharmaceutics

View full text Add to dashboard Cite

Section: Near Infrared-diffuse Reflectance (Nir-dr) Spectroscopymentioning

confidence: 99%

The human nail – Barrier characterisation and permeation enhancement

Walters¹,

Abdalghafor

Lane

2012

International Journal of Pharmaceutics

View full text Add to dashboard Cite

“…[20][21][22][23] Results from this experiment will be used in conjunction with our previous work [24][25][26] to aid the future design and development of a portable NIR spectroscopic device that would allow accurate, fast, and noninvasive in vivo measurements of skin hydration and water content.…”

Section: Introductionmentioning

confidence: 99%

Use of reflectance near-infrared spectroscopy to investigate the effects of daily moisturizer application on skin optical response and barrier function

Qassem

Kyriacou

2014

J. Biomed. Opt

View full text Add to dashboard Cite

Citation: Qassem, M. & Kyriacou, P. A. (2014). Use of reflectance near-infrared spectroscopy to investigate the effects of daily moisturizer application on skin optical response and barrier function. Journal of Biomedical Optics, 19(8), 087007. doi: 10.1117/1. JBO.19.8.087007 This is the accepted version of the paper.This version of the publication may differ from the final published version. Abstract. A number of noninvasive techniques and instruments have emerged over the years allowing much progress toward clarifying the structure and function of human skin and studying the effects of various applied substances. All of this research has provided great insight into the interactions between skin and various products through quantitative and qualitative measurements. Such methods include near-infrared spectroscopy (NIRS), a technique which has gained popularity over the years and has often been employed to accurately determine the moisture levels and water content of skin based on its sensitivity to hydrogen bonding. NIRS has also been applied in many studies to report the efficacy of moisturizing products and assess their benefits to the skin. However, many of these studies have reported an increase in skin water content following moisturizer application while some have challenged the benefits of long-term moisturizer use, particularly on normal skin, and even suggested that it can increase the skin's susceptibility to irritants. This paper reports the results of a pilot in vivo study carried out on the skin of 20 healthy volunteers, categorized into groups depending on their skin type and frequency of moisturizer use, in order to investigate the optical response of human skin after direct short-term contact with water followed by application of a moisturizer. The measurements were obtained using a highly advanced spectrophotometer in the region of 900 to 2100 nm equipped with a customized reflectance fiber optic handheld probe. Scatter graphs of group results and second derivative spectra have shown an interesting pattern between frequent users of moisturizers and individuals who do not use moisturizers, suggesting that long-term daily moisturization may have an effect on skin barrier function. The results also raise some questions regarding the optical characteristics of different skin types, as well as the varying response between different water bands in the NIR region. Future work will focus on gaining more knowledge about these subjects and obtaining results from a larger population, as well as performing statistical analysis through regression methods in order to further improve optical skin measurements. Permanent

show abstract

“…Water content increased markedly up to 16.6 wt% when ambient RH increased above 80%. Nail thickness appeared to have little effect on the amount of water in nails [18].…”

Section: Near-ir-diffuse Reflectance (Nir-dr) Spectroscopymentioning

confidence: 85%

“…Considering the fact that the viable nail is susceptible to direct changes in temperature [17] and humidity [18], the electrical studies may prove as a useful diagnostic biomedical tool.…”

Section: Dielectric Spectroscopymentioning

confidence: 99%

“…The latter part may be absorbed within the particles or be diffracted at grain boundaries, giving rise to diffusely scattered light in all directions. The potential of this technique to determine the water content of human nail plates was explored by Egawa et al [18]. NIR-DR spectra were collected from excised nail plates (in vitro), incubated at different relative humidity (1-99%) at 25°C as well as from viable (in vivo) fingernails.…”

Section: Near-ir-diffuse Reflectance (Nir-dr) Spectroscopymentioning

confidence: 99%

See 1 more Smart Citation

Structural and component mining of nails using bioengineering techniques

Thatai

Sapra

2016

Intern J of Cosmetic Sci

View full text Add to dashboard Cite

The human nail is one of the challenging membranes for the scientists to target and to improve the clinical efficacy of ungual formulations. The understanding of nail physiology, impact of hydration on its properties and presence of trace elements in nails as biomarkers has been explored by various researchers in clinical studies. Despite the importance of biophysical techniques for the assessment of structure and physiology of nail, minimum literature analyses biophysical, biochemical and bioanalytical approaches. However, nowadays scientists in bioengineering field are keen in developing non-invasive, reliable and reproducible techniques for the assessment of different anatomical and functional parameters of nails for testing of ungual products.

show abstract

Determining Water Content in Human Nails with a Portable Near-Infrared Spectrometer

Cited by 34 publications

References 22 publications

The human nail – Barrier characterisation and permeation enhancement

The human nail – Barrier characterisation and permeation enhancement

Use of reflectance near-infrared spectroscopy to investigate the effects of daily moisturizer application on skin optical response and barrier function

Structural and component mining of nails using bioengineering techniques

Contact Info

Product

Resources

About