Determining the Optimal Quantitative Threshold for Preoperative Albumin Level Before Elective Colorectal Surgery

Bendersky, Victoria A.; Sun, Zhifei; Adam, Mohamed A.; Rushing, Christel; Kim, Jina; Youngwirth, Linda M.; Turner, Megan C.; Migaly, John; Mantyh, Christopher R.

doi:10.1007/s11605-017-3370-9

Cited by 16 publications

(9 citation statements)

References 22 publications

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“…Based on a database including 16,145 colorectal surgical patients, it was found that patients with preoperative SA < 3.9gdL À1 were at higher risk of a major complication (OR 1.18, 95% CI 1.07-1.30, p ¼ 0.0007), any complication (OR 1.18, 95% CI 1.08-1.29, p ¼ 0.0002) and prolonged LOS. Interestingly, each decrease in SA by 0.5gdL -1 was associated with increased risk (Bendersky et al 2017). In our study, preoperative SA was found to be predictive of mortality and risk for reoperation (cut-off 4gdL À1 ) and of urinary tract infection (cut-off 3.8gdL À1 ).…”

Section: Discussionsupporting

confidence: 47%

Should we change reference range for serum albumin in major gastrointestinal surgery? Preoperative serum albumin as an important prognostic factor

Czempik

Czepczor

Czok

2019

Journal of Perioperative Practice

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Introduction The aim of the study was to analyse prognostic value of laboratory markers of nutritional status in gastrointestinal surgery. Methods We performed a retrospective analysis of clinical and laboratory data of 102 patients admitted to an Intensive Care Unit following elective gastrointestinal surgery. The outcome measures included hospital mortality, infectious complications, surgical complications and length of stay. Results Forty-eight patients had all three laboratory markers of nutritional status determined before surgery and these patients constituted our study group. We found correlations between preoperative serum albumin and hospital mortality, risk of reoperation and urinary tract infection. Preoperative total serum protein correlated with urinary tract infection. Total lymphocyte count was predictive of bacteraemia. No statistically significant correlations were found between markers of nutritional status and length of stay. Conclusions Serum albumin concentration at the lower limit is associated with increased mortality, reoperation, urinary tract infection. Total serum protein predicts urinary tract infection, whereas total lymphocyte count predicts bacteraemia.

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Section: Discussionsupporting

confidence: 47%

Should we change reference range for serum albumin in major gastrointestinal surgery? Preoperative serum albumin as an important prognostic factor

Czempik

Czepczor

Czok

2019

Journal of Perioperative Practice

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“…Our study findings have significant clinical implications, demonstrating the need to optimise nutrition in patients with IBD, who are often chronically malnourished during states of prolonged disease exacerbation. Although the prevalence of malnutrition in IBD by ICD coding from a representative in‐patient cohort of IBD patients is 5%‐10%, the probability of malnutrition just prior to IBD‐related surgery is likely much higher . Previous literature suggests that more than half of all patients may meet criteria for malnutriton at the time of IBD diagnosis .…”

Section: Discussionmentioning

confidence: 99%

“…Although the prevalence of malnutrition in IBD by ICD coding from a representative in-patient cohort of IBD patients is 5%-10%, 37 the probability of malnutrition just prior to IBD-related surgery is likely much higher. 38 Previous literature suggests that more than half of all patients may meet criteria for malnutriton at the time of IBD diagnosis. 39 Furthermore, it is likely that malnutrition especially in acute care settings may be under-reported and not diagnosed in patients with IBD.…”

Section: Discussionmentioning

confidence: 99%

Risk of post‐operative surgical site infections after vedolizumab vs anti‐tumour necrosis factor therapy: a propensity score matching analysis in inflammatory bowel disease

Park

Sceats

Dehghan

et al. 2018

Aliment Pharmacol Ther

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“…The preoperative serum albumin level is strongly associated with outcomes following various types of gastrointestinal surgery, including gastric, pancreatic, and colorectal surgery , as well as non‐gastrointestinal surgery . The association between serum albumin and IAI is controversial .…”

Section: Introductionmentioning

confidence: 99%

Preoperative serum albumin is associated with intra‐abdominal infection following major hepatectomy

Rungsakulkij

Vassanasiri

Tangtawee

et al. 2019

J Hepato Biliary Pancreat

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Background Major hepatectomy is a complex surgical procedure with high morbidity. Intra-abdominal infection (IAI) is common following hepatectomy and affects treatment outcomes. This study was performed to investigate perioperative factors and determine whether the preoperative serum albumin level is associated with IAI following major hepatectomy. Methods From January 2008 to December 2018, 268 patients underwent major hepatectomy. We retrospectively analyzed demographic data and preoperative and perioperative variables. IAI was defined as organ/space surgical site infection. Risk factors for IAI were analyzed by logistic regression analysis. Results In total, 268 patients were evaluated. IAI was observed in 38 patients (14.6%). The mortality rate in the IAI group was 15.7%. Multivariate logistic analysis confirmed that the serum albumin level (odds ratio 0.91; 95% confidence interval 0.84-0.97; P = 0.03) and operative duration (odds ratio 1.50; 95% confidence interval 1.18-1.91; P < 0.01) were independent factors associated with IAI. A logistic model using the serum albumin level and operative duration to estimate the probability of IAI was analyzed. The area under the receiver operating characteristic curve for predicting IAI was 0.78. ConclusionThe serum albumin level and operative duration were independent factors predicting IAI following major hepatectomy.

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Determining the Optimal Quantitative Threshold for Preoperative Albumin Level Before Elective Colorectal Surgery

Cited by 16 publications

References 22 publications

Should we change reference range for serum albumin in major gastrointestinal surgery? Preoperative serum albumin as an important prognostic factor

Should we change reference range for serum albumin in major gastrointestinal surgery? Preoperative serum albumin as an important prognostic factor

Risk of post‐operative surgical site infections after vedolizumab vs anti‐tumour necrosis factor therapy: a propensity score matching analysis in inflammatory bowel disease

Preoperative serum albumin is associated with intra‐abdominal infection following major hepatectomy

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