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Cited by 17 publications
(15 citation statements)
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References 50 publications
(54 reference statements)
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“…While this study represents the first evaluation of the genotoxic potential of extracts from the Tephrosia genus, other studies performed with plant species of the Fabaceae family and a variety of biological systems obtained similar results, i.e., an absence of genotoxicity (Macêdo et al, 2008;Zampini et al, 2008).…”
Section: Discussionsupporting
confidence: 69%
“…While this study represents the first evaluation of the genotoxic potential of extracts from the Tephrosia genus, other studies performed with plant species of the Fabaceae family and a variety of biological systems obtained similar results, i.e., an absence of genotoxicity (Macêdo et al, 2008;Zampini et al, 2008).…”
Section: Discussionsupporting
confidence: 69%
“…Several plants have been used as folk medicine for the treatment of several diseases (Melo-Reis et al, 2011), some of which, such as Solanum validinervium (Suarez et al, 2006), Morinda citrifolia (Brito et al, 2009) and Annona squamosa (Nandhakumar & Indumathi, 2012), showed highly interesting characteristics, while others, such as Bauhinia monandra (Macêdo et al, 2008), Alchornea grandulosa, A. castaneaefolia (Santos et al, 2010) and Cochlospermum regium (Castro et al, 2004;Andrade et al, 2008), proved to be genotoxic.…”
Section: Introductionmentioning
confidence: 99%
“…However, there are no data in the literature, at least of our knowledge, with regard to the cytotoxicity of this medicinal plant popularly used. Studies concerning the toxicity and mutagenicity of medicinal plants are needed to verify the efficacy and safety of their use in the treatment of some diseases (Macêdo et al, 2008;Ferreira et al, 2009). In this context, meristematic cells of Allium cepa are often used as a vegetal test system to indicate the genotoxic potential of the medicinal plant extracts.…”
Section: Introductionmentioning
confidence: 99%