2010
DOI: 10.1049/iet-syb.2009.0040
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Determining the distance to monotonicity of a biological network: a graph-theoretical approach

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Cited by 54 publications
(135 citation statements)
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“…The heuristic we have introduced in ref. 33 is, however, able to produce fairly tight upper and lower bounds for δ (henceforth δ up and δ low ), also for very large signed graphs. This local search algorithm is described in some detail in the SI Text and in ref.…”
Section: Computation Of Global Balancementioning
confidence: 99%
See 1 more Smart Citation
“…The heuristic we have introduced in ref. 33 is, however, able to produce fairly tight upper and lower bounds for δ (henceforth δ up and δ low ), also for very large signed graphs. This local search algorithm is described in some detail in the SI Text and in ref.…”
Section: Computation Of Global Balancementioning
confidence: 99%
“…This local search algorithm is described in some detail in the SI Text and in ref. 33. The outcome of the algorithm is a gauge transformation of the adjacency matrix J into the equivalent J σ :…”
Section: Computation Of Global Balancementioning
confidence: 99%
“…(2) is often considered as frustration index [26], true frustration, or merely frustration [20,27]. However, in this context, the frustration and its minimum are considered separately.…”
Section: Preliminaries a Notationsmentioning
confidence: 99%
“…If we set k = 2, the optimal solution is the best two-clustering of a graph where the number of inconsistent edges is equal to the distance of a graph from SB [= F 2 (G)]. Iacono et al proposed a graph-theoretic approach to approximate F 2 (G), which has been originally stated as "distance from monotonicity" for biological networks [27]; note that monotonicity has the same mathematical implication as SB. The algorithm has been further applied to social networks validating that their distance from SB is significantly lower than those of sign-shuffled counterparts [20,34].…”
Section: A Structural Balance and Clusteringmentioning
confidence: 99%
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