Dengen (Dillenia serrata) is an endemic plant found in Luwu Regency. Its primary utilization is still limited to the fruit as a food ingredient, such as dodol, though leaves and barks are often used as medicine. According to Santi , dengen leaves and bark contain large polyphenols. This study determines the sunscreen activity of the Dengen plant, specifically leaves and bark obtained from Malangke City in Luwu Regency. Also, the study aims to establish the part of the plant with great potential for sunscreen. The leaves and bark of the tree are extracted by maceration using 70% ethanol solvent. The determination of the SPF value was carried out in vitro based on the principle of measuring extraction absorption with a certain concentration at wavelengths of 290-320 nm. The ethanol extract of the bark is made with a concentration series of 100, 200, 300, 400, and 500 ppm, where 100 ppm produced an SPF value of 4,611. Furthermore, the ethanol extracts of the leaves were made in series 50, 100, 150, 200, 250 ppm, where 100 ppm produced an SPF value of 2. This study concluded that the ethanol extract of dengen bark has maximum sunscreen activity with a low concentration compared to ethanol leaves.