Determination of Uric Acid in Serum, with Use of Uricase and a Tribromophenol—Aminoantipyrine Chromogen

Kabasakalian, Peter; Kalliney, Sami; Westcott, Anita

doi:10.1093/clinchem/19.5.522

Cited by 88 publications

(24 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Meanwhile a single channel was previously fabricated and its operation demonstrated in the measurement of uric acid concentration (λ = 495 nm). The reagent used in those measurements was the infinity TM uric acid reagent from Sigma-Aldrich [8]. A 200 W quartz tungsten halogen lamp was used as the white light source for biosystem illumination.…”

Section: Resultsmentioning

confidence: 99%

An array of Fabry-Perot optical-channels for biological fluids analysis

Minas

Ribeiro

Martins

et al. 2004

Sensors and Actuators A: Physical

View full text Add to dashboard Cite

This paper describes a biosystem (biological system) used to measure the concentration of biochemical substances in urine, serum, plasma or cerebrospinal fluid. Rather than just one channel, it comprises 16 optical-channels that enable the measurement of the concentration of 16 different biochemical substances. An array of 16 optical filters based on Fabry-Perot thin-films optical resonators has been designed. Each optical-channel is sensitive in a single wavelength with a full-width-half-maximum (FWHM) of 7 nm. The filter fabrication requires only four masks, used with different etch time. A commercially available band-pass optical filter with a band-pass wavelength in 450-650 nm is used. The biosystem requires only a white light source for illumination due the use of selective optical filters.

show abstract

Section: Resultsmentioning

confidence: 99%

An array of Fabry-Perot optical-channels for biological fluids analysis

Minas

Ribeiro

Martins

et al. 2004

Sensors and Actuators A: Physical

View full text Add to dashboard Cite

show abstract

“…Ltd., Mumbai). The studied parameters were blood glucose [18] , urea [19] , creatinine [20] , total cholesterol [21] , high-density lipoprotein (HDL)-cholesterol [22] , triglyceride [23] , very-low-density lipoprotein (VLDL)-cholesterol, low-density lipoprotein (LDL)-cholesterol, total protein [24] , albumin, globulin [25] , alkaline phosphatase [26] , serum glutamic oxaloacetic transaminase (SGOT) [27] , serum glutamic pyruvic transaminase (SGPT) [28] , uric acid [29] , direct bilirubin [28] , total bilirubin [30] , and serum calcium [31] .…”

Section: Methodsmentioning

confidence: 99%

Acute and subchronic toxicity study of Tamra Bhasma (incinerated copper) prepared with and without Amritikarana

Chaudhari

Nariya

Galib

et al. 2016

Journal of Ayurveda and Integrative Medicine

View full text Add to dashboard Cite

BackgroundTamra Bhasma (TB) is one among herbo-metallic preparations extensively used in routine ayurvedic practice. In the present era, Bhasma preparations used in ayurvedic system of medicines are always under stern observations for containing heavy metals which may raise the question of safety aspect.ObjectiveIn the present study, TB prepared with and without Amritikarana was subjected to toxicity study to ascertain the role of Amritikarana on safety profile of TB in rats.Materials and methodsBoth the samples of TB were administered to rats for 28 consecutive days at the doses of 5.5, 27.5, and 55 mg/kg. The effects of both drugs were assessed on ponderal changes, hematological, serum biochemical, and histopathology of various organs.ResultsResults showed that both the samples of TB did not produce any sign and symptoms of toxicity at therapeutic dose level (5.5 mg/kg) and therapeutic equivalent dose (TED) × 5 (27.5 mg/kg) while at higher dose of TED × 10 (55 mg/kg) TB has mild toxicity in liver, kidney, heart, and thymus on repeated administration for 28 days in rats. The sample without Amritikarana has more magnitude of toxicity than the sample with Amritikarana.ConclusionFrom the present study, it is concluded that TB with Amritikarana was found to be relatively safer than TB without Amritikarana at different dose levels in rats and hence suggest for safely use in humans at therapeutic dose level. It proves the role of Amritikarana in the preparation of TB.

show abstract

“…The enzymatic method of Patton & Crouch (1977) was applied to estimate serum urea while kinetic method of Houot (1985) was used to calculate serum creatinine. The method of Kabasakalian et al (1973) was applied to determine serum uric acid while Ciarlone & Smudski (1977) method was used to estimate serotonin (5-hydroxytryptamine; 5-HT), norepinephrine (NE), and dopamine (DA) in brain cerebral cortex. Maruyama et al (1987) method was applied to estimate serum testosterone (Ts) and Dehydroepiandro-sterone sulfate (DHEA-SO 4 ) concentrations.…”

Section: Biochemical Analysismentioning

confidence: 99%

Acute and subacute toxicity of Ammi visnaga on rats

Koriem

Arbid

El-Attar

2019

Interdisciplinary Toxicology

View full text Add to dashboard Cite

Ammi visnaga (Av) is a source of khellin where a tea made from the fruit of this plant was used as herbal medicine for kidney stones in Egypt. In the present research, the acute and subacute toxicity studies with oral intake of 150, 300 and 600 mg/kg of Av seed ethanolic extract in rats were done. In acute toxicity test, 4 groups of rats (n = 6/group: 3 males and 3 females) were chosen and the first control group received tap water, while the other three groups received Av seed ethanolic extract dissolved in tap water at doses of 150, 300, and 600 mg/kg, and general behavior, adverse effects, and mortality were recorded for up to 14 days. In subacute toxicity study, 72 rats (36 males and 36 females) were divided into 4 major groups; group I received tap water (control group), while animals in groups II, III, and IV (test groups) received oral intake of Av seed ethanolic extract dissolved in tap water at doses of 150, 300 and 600 mg/kg bwt, respectively. Each of this major group was subdivided consequently into 3 subgroups (n = 6/group: 3 males and 3 females) where brain tissue, blood sample, body and organs weights were recorded at the beginning and then after two and four weeks of the experiment for the determination of hematological, biochemical and histopathological changes in tissues (liver, kidney, brain, spleen, heart, testis and ovary). With regard to acute toxicity, Av seed ethanolic extract did not induce any toxic effects or death or any organ toxicity. In subacute toxicity study; oral intake with Av seed ethanolic extract did not reveal any change in body and organs weights, hematological parameters, serum glucose and cholesterol, brain neurotransmitters, liver and kidney functions, male and female hormones. In conclusion, Av seed ethanolic extract is nontoxic to liver, kidney, brain, spleen, heart, testis and ovary.

show abstract

Determination of Uric Acid in Serum, with Use of Uricase and a Tribromophenol—Aminoantipyrine Chromogen

Cited by 88 publications

References 0 publications

An array of Fabry-Perot optical-channels for biological fluids analysis

An array of Fabry-Perot optical-channels for biological fluids analysis

Acute and subchronic toxicity study of Tamra Bhasma (incinerated copper) prepared with and without Amritikarana

Acute and subacute toxicity of Ammi visnaga on rats

Contact Info

Product

Resources

About