Determination of the Type of Pneumococcus in the Sputum of Lobar Pneumonia

Abstract

gross morbid changes. For several days before death, he had the facies of impending death. The poison was profound without being irritative. There was no associated delirium; there was none of the activity of meningeal irrita'Jon; there was not the reaction and collapse of hepatic or uremie toxemia. The forceful effects of asphyxia, noticed especially the day before death, puts the etiologic toxin in the class of potent chemicals.The kidney insufficiency probably helped to accumu¬ late the toxin, but, considered by itself, apparently played a minor rôle.The physical question of the small tumor acting as the starting point for intussusception is not uncom¬ mon.In the records of the McManes Laboratory of the University of Pennsylvania there are several similar cases. These are mostly secondary tumors, as carcinoma and one very interesting case of secondary hypernephroma. SUMMARY 1. The case illustrates a small adenoma of the jejunum as the starting point for an intussusception.2. This intussusception resulted in high obstruction of the intestine, with marked changes in the intestinal wall at this point.3. These intestinal changes produced a toxemia. 4. This toxemia was extremely potent, and ended in death.

Studies on a Paratyphoid Infection in Guinea Pigs

“…Absorption tests with Mouse Paratyphoid I and with Guinea Pig Paratyphoid 922 gave further proof of a close relationship between the two strains, if not of their actual identity. The indicated relationships are in harmony with the early work of Wherry (3) and the more recent work of Krumwiede, Valentine, and Kohn (11). The latter investigators studied the agglutinative affinities of fifteen strains from guinea pigs.…”

Variations in Typhoid Bacilli

“…Having obtained this information concering certain related species of bacteria it should usually be easy to select those sugars which would yield the most reliable information for the differentiation of the species. Thus, Krumwiede (1918), and quite recently Jordan also, have recommended acid production in rhamnose broth as the most fundamental method of differentiating the paratyphoids from Bact. typhosum.…”

The Precipitin Reaction of Antipneumococcus Sera

“…(Received for publication, September 2, 1927. ) In the diagnosis of infectious disease precipitin and agglutinin reactions have assisted in the identification of the invading organism, when the patient's serum has been tested with suspected organisms or when antigenic material from the patient (1) has been tested against antisera.…”