Determination of the residue dynamics and dietary risk of thiamethoxam and its metabolite clothianidin in citrus and soil by LC-MS/MS

Gui, Ting; Jia, Gui F; Xu, Jin; Ge, Shi J; Long, Xiao F; Zhang, Yu P; Hu, De Y

doi:10.1080/03601234.2019.1571361

Cited by 30 publications

(17 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The half-lives were in the range from 1.3 to 1.6 days. The results were similar to the half-lives of thiamethoxam in tomato (2.34 days) [ 24 ], goji berry [ 10 ] (1.01–1.08 days), cowpea [ 11 ] (0.8–1.6 days), and citrus [ 16 ] (1.9 days), reported by previous studies. For the Shandong site, the dissipation rate of thiamethoxam was more rapid than at the other three sites.…”

Section: Resultssupporting

confidence: 90%

“…Dissipation study was to investigate the dissipation behavior of thiamethoxam. The terminal study was conducted to study residual concentrations of thiamethoxam, based on which acute dietary intake is calculated [ 16 ]. 8 test sites were located in Hohhot city in Inner Mongolia Autonomous Region, Taiyuan city in Shanxi province (dissipation), Beijing city, Jinan city in Shandong province (dissipation), Suzhou city in Anhui province (dissipation), Changsha city in Hunan province, Guiyang city in Guizhou province, and Foshan city in Guangdong province (dissipation).…”

Section: Methodsmentioning

confidence: 99%

“…To date, many studies have been carried out on the dissipation behavior and dietary risk assessment of thiamethoxam and clothianidin on different matrices, including gogi berry [ 10 ], cowpea [ 11 , 12 ], strawberry [ 13 ], apple [ 14 , 15 ], citrus [ 16 ], mango [ 17 ], wheat [ 18 ], lettuce [ 18 ], and tomato [ 18 ]. For example, Rahman et al found that half-lives on Swiss chard were in reverse order of initial deposition [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Dissipation Behavior and Acute Dietary Risk Assessment of Thiamethoxam and Its Metabolite Clothianidin on Spinach

et al. 2022

View full text Add to dashboard Cite

Thiamethoxam and its metabolite clothianidin residues pose a potential threat to human health. This study aims to investigate the residue behavior and acute dietary risk assessment of thiamethoxam and clothianidin on spinach. Thiamethoxam and clothianidin were extracted using a quick, easy, cheap, effective, rugged, safe (QuEChERS) method and analyzed using liquid chromatography-tandem mass spectrometry (LC-MS/MS). At spike levels from 0.01 to 5 mg kg−1, the average recoveries of both analytes were in the range of 94.5–105.5%, with relative standard deviations (RSDs) of 3.8–10.9%. The dissipation behavior of thiamethoxam followed first-order kinetics, with half-lives of ≤1.6 days. Clothianidin appeared readily as a plant metabolite with highest level exhibited during 3 to 5 days after application. Temperature and light may be two main factors for degradation of thiamethoxam. Besides, acute risk assessment of thiamethoxam and clothianidin was evaluated with risk quotients (RQs) <100%, which suggested a low health risk for all consumer groups of Chinese residents.

show abstract

Section: Resultssupporting

confidence: 90%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Dissipation Behavior and Acute Dietary Risk Assessment of Thiamethoxam and Its Metabolite Clothianidin on Spinach

et al. 2022

View full text Add to dashboard Cite

show abstract

“…This may be related to the environment condition, crop varieties, the weather, application time and other factors. 14,17,18,30 The residue level of acephate and its metabolite methamidophos in glasshouse pakchoi was also higher than in open-field pakchoi. 31 Currently, the MRLs for thiamethoxam and clothianidin in Chinese kale have not yet been established in China.…”

Section: Residue Distributions Of Thiamethoxam In Chinese Kalementioning

confidence: 94%

Monitoring residue levels and dietary risk assessment of thiamethoxam and its metabolite clothianidin for Chinese consumption of Chinese kale

Chen

Zhang

et al. 2021

J Sci Food Agric

View full text Add to dashboard Cite

BACKGROUND: Thiamethoxam is widely used to control pests in Chinese kale, popularly consumed leafy vegetables. The potential risk to the environment and human health has aroused much public concern. Therefore, it is important to investigate the degradation behavior, residue distribution and dietary risk assessment of thiamethoxam in Chinese kale.RESULTS: A sensitive analytical method for determination of thiamethoxam and its metabolite clothianidin residue in Chinese kale was established and validated through a quick, easy, cheap, effective, rugged, and safe (QuEChERS) technique with ultraperformance liquid chromatography tandem mass spectrometry (UPLC-MS/MS). The recoveries were 85.4-101.2% for thiamethoxam and 79.5-108.1% for clothianidin, with the relative standard deviations (RSDs) of 0.9-10.2% and 1.8-6.0%, respectively. For the dissipation kinetics, the data showed that thiamethoxam in Chinese kale was degraded with the half-lives of 4.1 to 4.5 days. In the terminal residue experiments, the residues of thiamethoxam were 0.017-0.357 mg kg −1 after application 2-3 times with a preharvest interval (PHI) of 7 days under the designed dosages. The chronic and acute dietary exposure assessment risk quotient (RQ) values of thiamethoxam in Chinese kale for different Chinese consumers were 0.08-0.19% and 0.05-0.12%, respectively, and those of clothianidin were 0.01-0.04% and 0.02-0.04%, respectively, all of the RQ values were lower than 100%.CONCLUSION: Thiamethoxam in Chinese kale was rapidly degraded following first-order kinetics models. The dietary risk of thiamethoxam and clothianidin through Chinese kale was negligible to consumers. The results from this study are important reference for Chinese governments to developing criteria for the safe and rational use of thiamethoxam, setting maximum residue levels (MRLs), monitoring the quality safety of agricultural products and protecting consumer health.

show abstract

“…For long-term risk assessment, the estimated daily intake (EDI), HQ (Hazard Quotient), and Hazard Index (HI) were determined according to the following equations (Cámara et al, 2020;Gui et al, 2019;Milinčić et al, 2020;Pallarés et al, 2020;Tandon, 2016;Yang et al, 2020 MRL of chlorpyrifos-methyl, dimethoate, permethrin, iprodione, metalaxyl, and propargite in parsley was considered as 0.02, 0.02, 0.05, 0.02, 3, and 0.02 mg/kg, respectively (Commission Regulation, 2017a, 2017b, 2017c, 2018a, 2018b.…”

Section: Risk Assessmentmentioning

confidence: 99%

Persistence and dissipation behavior of pesticide residues in parsley (Petroselinum crispum) under field conditions

Heshmati

Komacki

Nazemi

et al. 2020

qas

View full text Add to dashboard Cite

The residue level, dissipation behavior, and dietary intake risk of chlorpyrifos-methyl, dimethoate, permethrin, iprodione, metalaxyl, and propargite in parsley (Petroselinum crispum) were investigated under field conditions. Extraction and determination of pesticide residues were carried out by a quick, easy, cheap, effective, rugged, and safe (QuEChERS) method and a gas chromatography/tandem mass spectrometry (GC/MS/MS) system, respec-tively. Dissipation of chlorpyrifos-methyl, dimethoate, permethrin, iprodione, metalaxyl, and propargite in pars-ley followed the first-order kinetics with a half-life (t1/2) of 3.33, 3.30, 2.94, 3.52, 4.10, and 3.38 days, respectively. Based on the dissipation pattern and the maximum residue limits (MRL), preharvest intervals (PHI) of 25, 13, 18, 24, 1, and 16 days are suggested for chlorpyrifos-methyl, dimethoate, permethrin, iprodione, metalaxyl, and propargite in parsley, respectively. The estimated daily intake (EDI) of pesticides ranged from 7.37E-05 (dimeth-oate) to 8.00E-04 (metalaxyl) mg/kg. The chronic risk assessment showed that the hazard quotient (HQ) was <1 and Hazard Index (HI, indicating the cumulative exposure to pesticide residues) was <100%, demonstrating that an intake of pesticide residues from parsley was safe for humans.

show abstract

Determination of the residue dynamics and dietary risk of thiamethoxam and its metabolite clothianidin in citrus and soil by LC-MS/MS

Cited by 30 publications

References 20 publications

Dissipation Behavior and Acute Dietary Risk Assessment of Thiamethoxam and Its Metabolite Clothianidin on Spinach

Dissipation Behavior and Acute Dietary Risk Assessment of Thiamethoxam and Its Metabolite Clothianidin on Spinach

Monitoring residue levels and dietary risk assessment of thiamethoxam and its metabolite clothianidin for Chinese consumption of Chinese kale

Persistence and dissipation behavior of pesticide residues in parsley (Petroselinum crispum) under field conditions

Contact Info

Product

Resources

About